Anti-Cdc6抗体(ab125195)
Key features and details
- Rabbit polyclonal to Cdc6
- Suitable for: IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-Cdc6抗体
参阅全部 Cdc6 一抗 -
描述
兔多克隆抗体to Cdc6 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Chimpanzee, Gorilla -
免疫原
Synthetic peptide, corresponding to a region within N terminal amino acids 1-50 of Human Cdc6 (NP_001245.1).
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阳性对照
- Human Breast Carcinoma, Colon Carcinoma, Non-Small Cell Lung Cancer, Ovarian Carcinoma and Prostate Carcinoma tissues; Mouse Colon Carcinoma CT26, Renal Cell Carcinoma and Teratoma tissues.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 99% Tris buffered saline, 0.1% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab125195 was affinity purified using an epitope specific to Cdc6 immobilized on a solid support. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab125195于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Likely to work with frozen sections
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说明 |
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IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Likely to work with frozen sections |
靶标
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功能
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. -
序列相似性
Belongs to the CDC6/cdc18 family. -
细胞定位
Nucleus. Cytoplasm. The protein is nuclear in G1 and cytoplasmic in S-phase cells. - Information by UniProt
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数据库链接
- Entrez Gene: 990 Human
- Entrez Gene: 23834 Mouse
- Omim: 602627 Human
- SwissProt: Q99741 Human
- SwissProt: O89033 Mouse
- Unigene: 405958 Human
- Unigene: 20912 Mouse
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别名
- Cdc 18L antibody
- Cdc 6 antibody
- CDC18 (cell division cycle 18, S.pombe, homolog) like antibody
see all
图片
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ab125195 at 1/100 dilution staining Cdc6 in Formalin-Fixed, Paraffin-Embedded Human colon carcinoma tissue by Immunohistochemistry.
Detection: DAB staining. -
ab125195 at 1/100 dilution staining Cdc6 in Formalin-Fixed, Paraffin-Embedded Mouse teratoma tissue by Immunohistochemistry.
Detection: DAB staining.
数据表及文件
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Datasheet download
文献 (1)
ab125195 被引用在 1 文献中.
- Wang X et al. Targeting RNA helicase DHX33 blocks Ras-driven lung tumorigenesis in vivo. Cancer Sci 111:3564-3575 (2020). PubMed: 32767810