概述

  • 产品名称Anti-CDC45L抗体
    参阅全部 CDC45L 一抗
  • 描述
    小鼠单克隆抗体to CDC45L
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-567 of Human CDC45L

性能

应用

Our Abpromise guarantee covers the use of ab56476 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Required for initiation of chromosomal DNA replication.
    • 组织特异性Widely expressed, highest levels are found in adult testis and thymus and in fetal liver.
    • 序列相似性Belongs to the CDC45 family.
    • 发展阶段Transcript peaks at G1-S transition, but total protein remains constant throughout the cell cycle. Expressed in multiple tissues during embryogenesis, including neural crest-derived structures.
    • 细胞定位Cytoplasm. Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CDC 45 antibody
      • CDC 45L antibody
      • CDC45 (cell division cycle 45, S.cerevisiae homolog) like antibody
      • CDC45 antibody
      • CDC45 cell division cycle 45 like antibody
      • CDC45 like antibody
      • CDC45 related protein antibody
      • CDC45_HUMAN antibody
      • CDC45L2 antibody
      • Cell division control protein 45 homolog antibody
      • Cell division cycle 45 like 2 antibody
      • Cell division cycle 45 like antibody
      • PORC PI 1 antibody
      • PORC-PI-1 antibody
      see all

    Anti-CDC45L antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab56476 CDC45L antibody at 1ug/ml. Predicted band size of immunogen is 88 kDa

    Anti-CDC45L antibody (ab56476)参考文献

    This product has been referenced in:
    • Mazurek A  et al. DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells. Cancer Discov 2:812-25 (2012). Human . Read more (PubMed: 22750847) »
    • Kawabata T  et al. A reduction of licensed origins reveals strain-specific replication dynamics in mice. Mamm Genome 22:506-17 (2011). WB ; Mouse . Read more (PubMed: 21611832) »

    See all 2 Publications for this product

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