Anti-CDC42 binding protein kinase alpha抗体(ab113710)

概述

  • 产品名称Anti-CDC42 binding protein kinase alpha抗体
    参阅全部 CDC42 binding protein kinase alpha 一抗
  • 描述
    山羊多克隆抗体to CDC42 binding protein kinase alpha
  • 经测试应用适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide (

    SGEVRLRQLEQFI

    -C) corresponding to N terminal amino acids 2-14 of Human CDC42 binding protein kinase alpha.

  • 阳性对照
    • Human Brain Cerebellum and Human Small Intestine Submucosal Plexus tissue.

性能

应用

Our Abpromise guarantee covers the use of ab113710 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/16000.
IHC-P Use a concentration of 3.75 µg/ml.

靶标

  • 功能May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.
  • 组织特异性Abundant in the heart, brain, skeletal muscle, kidney, and pancreas, with little or no expression in the lung and liver.
  • 序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 CNH domain.
    Contains 1 CRIB domain.
    Contains 1 PH domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 protein kinase domain.
  • 细胞定位Cytoplasm. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A930014J19Rik antibody
    • CDC42 binding protein kinase alpha (DMPK like) antibody
    • CDC42 binding protein kinase alpha antibody
    • CDC42 binding protein kinase alpha dmpk like antibody
    • CDC42 binding protein kinase beta antibody
    • CDC42-binding protein kinase alpha antibody
    • CDC42BPA antibody
    • DKFZp686L1738 antibody
    • DKFZp686P1738 antibody
    • DMPK like antibody
    • DMPK-like alpha antibody
    • FLJ23347 antibody
    • KIAA0451 antibody
    • MGC189823 antibody
    • MRCK alpha antibody
    • mrck antibody
    • mrcka antibody
    • MRCKA_HUMAN antibody
    • Myotonic dystrophy kinase related CDC42 binding protein kinase alpha antibody
    • Myotonic dystrophy kinase-related CDC42-binding kinase alpha antibody
    • Myotonic dystrophy protein kinase-like alpha antibody
    • OTTHUMP00000035727 antibody
    • OTTHUMP00000035728 antibody
    • OTTHUMP00000035729 antibody
    • OTTHUMP00000035730 antibody
    • pk428 antibody
    • RP5-1087E8.4 antibody
    • Ser thr protein kinase PK428 antibody
    • Ser thr protein kinase related to the myotonic dystrophy protein kinase antibody
    • Serine/threonine protein kinase MRCK alpha antibody
    • Serine/threonine-protein kinase MRCK alpha antibody
    see all

Anti-CDC42 binding protein kinase alpha antibody 图像

  • ab113710 at 3.75 µg/ml staining CDC42 binding protein kinase alpha in Formalin-Fixed, Paraffin-Embedded Human brain cerebellum tissue.
  • ab113710 at 3.75 µg/ml staining CDC42 binding protein kinase alpha in Formalin-Fixed, Paraffin-Embedded Human small intestine, submucosal plexus tissue.

Anti-CDC42 binding protein kinase alpha antibody (ab113710)参考文献

ab113710 has not yet been referenced specifically in any publications.

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