概述

  • 产品名称Anti-Cdc37抗体[EPR4934]
    参阅全部 Cdc37 一抗
  • 描述
    兔单克隆抗体[EPR4934] to Cdc37
  • 经测试应用适用于: WB, IP, IHC-P, Flow Cytmore details
    不适用于: ICC
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human Cdc37.

  • 阳性对照
    • Jurkat, A431, K562, LnCaP and SW480 cell lysates; Human breast ductal infiltrating carcinoma
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

应用

Our Abpromise guarantee covers the use of ab109419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 44 kDa).
IP 1/10 - 1/100.
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for ICC.
  • 靶标

    • 功能Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
    • 序列相似性Belongs to the CDC37 family.
    • 翻译后修饰Constitutively sumoylated by UBE2I.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CDC 37 antibody
      • Cdc37 antibody
      • CDC37 cell division cycle 37 homolog antibody
      • CDC37 cell division cycle 37 S cerevisiae homolog antibody
      • CDC37 cell division cycle 37, S cerevisiae, homolog of antibody
      • Cdc37 homolog antibody
      • CDC37 protein antibody
      • CDC37_HUMAN antibody
      • CDC37A antibody
      • cell division cycle 37 antibody
      • Cell division cycle 37 homolog antibody
      • Hsp90 chaperone protein kinase targeting subunit antibody
      • Hsp90 chaperone protein kinase targeting subunit p50Cdc37 antibody
      • Hsp90 chaperone protein kinase-targeting subunit antibody
      • Hsp90 co chaperone Cdc37 antibody
      • Hsp90 co-chaperone Cdc37 antibody
      • p50 antibody
      • p50Cdc37 antibody
      • S cerevisiae hypothetical protein CDC37 antibody
      see all

    Anti-Cdc37 antibody [EPR4934] 图像

    • All lanes : Anti-Cdc37 antibody [EPR4934] (ab109419) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : A431 cell lysate
      Lane 3 : K562 cell lysate
      Lane 4 : LnCaP cell lysate
      Lane 5 : SW480 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 44 kDa
    • ab109419, at 1/250 dilution, staining Cdc37 in Human breast ductal infiltrating carcinoma by Immunohistochemistry.

    Anti-Cdc37 antibody [EPR4934] (ab109419)参考文献

    This product has been referenced in:
    • Synoradzki K & Bieganowski P Middle domain of human Hsp90 isoforms differentially binds Aha1 in human cells and alters Hsp90 activity in yeast. Biochim Biophys Acta 1853:445-52 (2015). Read more (PubMed: 25486457) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab109419.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"