概述

  • 产品名称Anti-CD97抗体
    参阅全部 CD97 一抗
  • 描述
    兔多克隆抗体to CD97
  • 特异性Immunogen is 100% homologous in human isoforms a, b, c and d.
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human, Chimpanzee
    预测可用于: Monkey
  • 免疫原

    A portion of amino acids 220-270 of human CD97

  • 阳性对照
    • K562 cell lysate; human spleen tissue

性能

应用

Our Abpromise guarantee covers the use of ab72107 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 92 kDa (predicted molecular weight: 92 kDa).
IHC-P Use a concentration of 10 µg/ml.

靶标

  • 功能Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
  • 组织特异性Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompagnied by detectable levels of soluble CD97 in the synovial fluid.
  • 序列相似性Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 5 EGF-like domains.
    Contains 1 GPS domain.
  • 结构域The first two EGF domains mediate the interaction with DAF. A third tandemly arranged EGF domain is necessary for the structural integrity of the binding region.
    Binding to chondroitin sulfate is mediated by the fourth EGF domain.
  • 翻译后修饰Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.
  • 细胞定位Cell membrane and Secreted > extracellular space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ADGRE5 antibody
    • Adhesion G protein-coupled receptor E5 antibody
    • CD 97 antibody
    • CD_antigen=CD97 antibody
    • CD97 antibody
    • CD97 antigen antibody
    • CD97 antigen subunit beta antibody
    • CD97 molecule antibody
    • CD97_HUMAN antibody
    • Leukocyte antigen CD97 antibody
    • Seven span transmembrane protein antibody
    • Seven transmembrane helix receptor antibody
    • Seven transmembrane heterodimeric receptor associated with inflammation antibody
    • TM7LN 1 antibody
    • TM7LN1 antibody
    see all

Anti-CD97 antibody 图像

  • All lanes : Anti-CD97 antibody (ab72107) at 2 µg/ml

    Lane 1 : K562 cell lysate
    Lane 2 : K562 cell lysate with immunizing peptide


    Predicted band size : 92 kDa
    Observed band size : 75 kDa (why is the actual band size different from the predicted?)
  • Analysis of CD97 expression in human spleen tissue using ab72107 at 10ug/ml.

Anti-CD97 antibody (ab72107)参考文献

ab72107 has not yet been referenced specifically in any publications.

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