RabMAb

Anti-CD89抗体[EPR4622(2)] (ab124717)

概述

  • 产品名称Anti-CD89抗体[EPR4622(2)]
    参阅全部 CD89 一抗
  • 描述
    兔单克隆抗体[EPR4622(2)] to CD89
  • 经测试应用适用于: WB, IP, IHC-P, Flow Cyt, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues near the C-terminus of Human CD89.

  • 阳性对照
    • U937, K562, Jurkat, and HL-60 cell lysates; Human tonsil tissue
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 纯度Tissue culture supernatant
  • 克隆单克隆
  • 克隆编号EPR4622(2)
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab124717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 32 kDa.
IP 1/10 - 1/100.
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

ICC/IF 1/500 - 1/1000.

靶标

  • 功能Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
  • 组织特异性Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
  • 序列相似性Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD89 antibody
    • Fc alpha receptor antibody
    • Fc fragment of IgA, receptor for antibody
    • FCAR antibody
    • FCAR_HUMAN antibody
    • IgA Fc receptor antibody
    • Immunoglobulin alpha Fc receptor antibody
    see all

Anti-CD89 antibody [EPR4622(2)] 图像

  • All lanes : Anti-CD89 antibody [EPR4622(2)] (ab124717) at 1/1000 dilution

    Lane 1 : U937 cell lysates
    Lane 2 : K562 cell lysates
    Lane 3 : Jurkat cell lysates
    Lane 4 : HL-60 cell lysates

    Lysates/proteins at 10 µg per lane.

    Secondary
    HRP labelled goat anti-rabbit at 1/2000 dilution

    Predicted band size : 32 kDa
  • ab124717, at 1/100, staining CD89 in paraffin embedded Human tonsil tissue by Immunohistochemistry.

Anti-CD89 antibody [EPR4622(2)] (ab124717)参考文献

ab124717 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"