概述

  • 产品名称Anti-CD80抗体[16-10A1] (Biotin)
    参阅全部 CD80 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[16-10A1] to CD80 (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    CHO cell line transfected with Mouse CD80

  • 阳性对照
    • Activated C57Bl/6 splenocyte suspensions

性能

应用

Our Abpromise guarantee covers the use of ab93506 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use 0.125µg for 105 to 108 cells in a final volume of 100µl.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
    • 组织特异性Expressed on activated B-cells, macrophages and dendritic cells.
    • 序列相似性Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Activation B7-1 antigen antibody
      • B lymphocyte activation antigen B7 antibody
      • B7 antibody
      • B7-1 antibody
      • B7-1 antigen antibody
      • B7.1 antibody
      • BB1 antibody
      • CD28 antigen ligand 1 antibody
      • CD28LG antibody
      • CD28LG1 antibody
      • CD80 antibody
      • CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) antibody
      • CD80 antigen antibody
      • CD80 molecule antibody
      • CD80_HUMAN antibody
      • Costimulatory factor CD80 antibody
      • costimulatory molecule variant IgV-CD80 antibody
      • CTLA-4 counter-receptor B7.1 antibody
      • LAB7 antibody
      • T-lymphocyte activation antigen CD80 antibody
      see all

    Anti-CD80 antibody [16-10A1] (Biotin) 图像

    • Flow cytometry image showing staining of 3-day LPS activated C57Bl/6 splenocytes with 0.06 µg of a Biotin Armenian Hamster IgG Isotype Control (open histogram) and 0.06 µg of ab93506 (colored histogram) followed by Streptavidin-PE (Phycoerythryn). Total viable cells were used for analysis.

    Anti-CD80 antibody [16-10A1] (Biotin) (ab93506)参考文献

    This product has been referenced in:
    • Zhang B  et al. NF-kappaB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells. J Biol Chem 281:38617-24 (2006). Read more (PubMed: 17046818) »
    • Odobasic D  et al. Glomerular expression of CD80 and CD86 is required for leukocyte accumulation and injury in crescentic glomerulonephritis. J Am Soc Nephrol 16:2012-22 (2005). Read more (PubMed: 15944341) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"