概述

  • 产品名称Anti-CD80抗体[16-10A1]
    参阅全部 CD80 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[16-10A1] to CD80
  • 经测试应用适用于: IP, IHC-Fr, Flow Cyt, Blockingmore details
  • 种属反应性
    与反应: Mouse, Dog
  • 免疫原

    CD80-transfected CHO cell line.

性能

应用

Our Abpromise guarantee covers the use of ab106162 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at an assay dependent dilution.
IHC-Fr Use at an assay dependent dilution.
Flow Cyt Use a concentration of 6 µg/ml.
Blocking Use at an assay dependent dilution.

靶标

  • 功能Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
  • 组织特异性Expressed on activated B-cells, macrophages and dendritic cells.
  • 序列相似性Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Activation B7-1 antigen antibody
    • B lymphocyte activation antigen B7 antibody
    • B7 antibody
    • B7-1 antibody
    • B7-1 antigen antibody
    • B7.1 antibody
    • BB1 antibody
    • CD28 antigen ligand 1 antibody
    • CD28LG antibody
    • CD28LG1 antibody
    • CD80 antibody
    • CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) antibody
    • CD80 antigen antibody
    • CD80 molecule antibody
    • CD80_HUMAN antibody
    • Costimulatory factor CD80 antibody
    • costimulatory molecule variant IgV-CD80 antibody
    • CTLA-4 counter-receptor B7.1 antibody
    • LAB7 antibody
    • T-lymphocyte activation antigen CD80 antibody
    see all

Anti-CD80 antibody [16-10A1] (ab106162)参考文献

This product has been referenced in:
  • Mukherjee S  et al. Modulation of cell cycle progression by CTLA4-CD80/CD86 interactions on CD4+ T cells depends on strength of the CD3 signal: critical role for IL-2. J Leukoc Biol 80:66-74 (2006). Read more (PubMed: 16624934) »
  • Odobasic D  et al. Glomerular expression of CD80 and CD86 is required for leukocyte accumulation and injury in crescentic glomerulonephritis. J Am Soc Nephrol 16:2012-22 (2005). Read more (PubMed: 15944341) »

See all 6 Publications for this product

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