Anti-CD8 alpha抗体[76-2-11] (Phycoerythrin) (ab25414)

概述

  • 产品名称Anti-CD8 alpha抗体[76-2-11] (Phycoerythrin)
    参阅全部 CD8 alpha 一抗
  • 描述
    小鼠单克隆抗体[76-2-11] to CD8 alpha (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性ab25414 recognises CD8a.
  • 经测试应用适用于: Flow Cyt, IP, Functional Studiesmore details
  • 种属反应性
    与反应: Pig
  • 免疫原

    The details of the immunogen for this antibody are not available.

性能

应用

Our Abpromise guarantee covers the use of ab25414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
IP
Functional Studies
  • 应用说明Flow Cyt: Use 0.2µg for 106 cells.
    FuncS (cytotoxicity assays): Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
    • 疾病相关Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
    • 序列相似性Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 翻译后修饰All of the five most carboxyl-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not.
    • 细胞定位Secreted and Cell membrane.
    • Information by UniProt
    • 别名
      • alpha polypeptide (p32) antibody
      • CD8 antibody
      • CD8 antigen alpha polypeptide antibody
      • CD8 antigen alpha polypeptide (p32) antibody
      • CD8a antibody
      • CD8A antigen antibody
      • CD8A molecule antibody
      • CD8A_HUMAN antibody
      • Leu2 antibody
      • Leu2 T lymphocyte antigen antibody
      • Ly3 antibody
      • LYT3 antibody
      • MAL antibody
      • OKT8 T cell antigen antibody
      • OTTHUMP00000160760 antibody
      • OTTHUMP00000160764 antibody
      • OTTHUMP00000203528 antibody
      • OTTHUMP00000203721 antibody
      • p32 antibody
      • T cell antigen Leu2 antibody
      • T cell co receptor antibody
      • T-cell surface glycoprotein CD8 alpha chain antibody
      • T-lymphocyte differentiation antigen T8/Leu-2 antibody
      • T8 T cell antigen antibody
      • T8/Leu-2 T-lymphocyte differentiation antigen antibody
      see all

    Anti-CD8 alpha antibody [76-2-11] (Phycoerythrin) 图像

    • ab25414 staining Pig peripheral blood mononuclear cells. 0.2µg antibody was used for 106 cells.

    Anti-CD8 alpha antibody [76-2-11] (Phycoerythrin) (ab25414)参考文献

    ab25414 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab25414.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"