概述

  • 产品名称
  • 描述
    兔多克隆抗体to CD73
  • 经测试应用
    适用于: ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH corrresponding to a region from the C-terminal region of Human CD73 protein

  • 阳性对照
    • Human placenta tissue and mouse brain tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab115289 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Predicted molecular weight: 63 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
  • 疾病相关
    Defects in NT5E are the cause of calcification of joints and arteries (CAJA) [MIM:211800]. A condition characterized by adult-onset calcification of the lower extremity arteries, including the iliac, femoral and tibial arteries, and hand and foot capsule joints. Age of onset has been reported as early as the second decade of life, usually involving intense joint pain or calcification in the hands.
  • 序列相似性
    Belongs to the 5'-nucleotidase family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5' NT antibody
    • 5' nucleotidase (CD73) antibody
    • 5' nucleotidase precursor antibody
    • 5' nucleotidase, ecto antibody
    • 5' nucleotidase, ecto (CD73) antibody
    • 5'-NT antibody
    • 5'-nucleotidase antibody
    • 5NTD_HUMAN antibody
    • CD73 antibody
    • CD73 antigen antibody
    • E5NT antibody
    • Ecto 5' nucleotidase antibody
    • Ecto-5'-nucleotidase antibody
    • eN antibody
    • eNT antibody
    • NT antibody
    • NT5 antibody
    • NT5E antibody
    • NTE antibody
    • Purine 5 Prime Nucleotidase antibody
    see all

Anti-CD73 antibody 图像

  • Immunohistochemistry image of formalin-fixed, paraffin-embedded Human placenta tissue stained with ab115289 at 10 µg followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Anti-CD73 antibody (ab115289) + Mouse brain tissue lysate

    Predicted band size : 63 kDa

Anti-CD73 antibody (ab115289)参考文献

This product has been referenced in:
  • Eirin A  et al. Integrated transcriptomic and proteomic analysis of the molecular cargo of extracellular vesicles derived from porcine adipose tissue-derived mesenchymal stem cells. PLoS One 12:e0174303 (2017). Read more (PubMed: 28333993) »
  • Yu YI  et al. Ecto-5'-nucleotidase expression is associated with the progression of renal cell carcinoma. Oncol Lett 9:2485-2494 (2015). Read more (PubMed: 26137095) »

See all 3 Publications for this product

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