Anti-CD72.1抗体[10-1.D.2] (Phycoerythrin) (ab25624)

概述

  • 产品名称Anti-CD72.1抗体[10-1.D.2] (Phycoerythrin)
    参阅全部 CD72.1 一抗
  • 描述
    小鼠单克隆抗体[10-1.D.2] to CD72.1 (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用适用于: Flow Cyt, Blockingmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Tissue/ cell preparation: DBA/2 mouse spleen cells.

  • 常规说明


    This antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However the antibody can itself trigger a positive signal by binding CD72. This antibody has also been shown to be useful in proliferation assays.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 16% Sucrose, PBS and stabilising agent.
  • Concentration information loading...
  • 纯度Protein A purified
  • Primary antibody说明This antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However the antibody can itself trigger a positive signal by binding CD72. This antibody has also been shown to be useful in proliferation assays.
  • 克隆单克隆
  • 克隆编号10-1.D.2
  • 同种型IgG2b
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab25624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.2µg for 106 cells.
Blocking Use at an assay dependent dilution.

靶标

  • 相关性Murine CD72.1/Lyb2.1, a type II integral membrane glycoprotein and a member of the C lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb2.1 allotype. CD72.1 is the ligand of CD5 (Ly1) which is distributed on all T cells and a small number of B cells.
  • 细胞定位Type II membrane protein.
  • 数据库链接
  • 别名
    • CD72 antigen antibody
    • Ly19 antibody
    • Ly32 antibody
    • LYB2 antibody
    • Lym19 antibody
    see all

Anti-CD72.1 antibody [10-1.D.2] (Phycoerythrin) 图像

Anti-CD72.1 antibody [10-1.D.2] (Phycoerythrin) (ab25624)参考文献

This product has been referenced in:
  • Mankaï A  et al. Purine-rich box-1-mediated reduced expression of CD20 alters rituximab-induced lysis of chronic lymphocytic leukemia B cells. Cancer Res 68:7512-9 (2008). Flow Cyt ; Human . Read more (PubMed: 18794139) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"