Anti-CD70抗体[TAN 1-7] (ab108482)
Key features and details
- Rat monoclonal [TAN 1-7] to CD70
- Suitable for: ELISA, ICC/IF, Flow Cyt
- Reacts with: Mouse
- Isotype: IgG2a
概述
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产品名称
Anti-CD70抗体[TAN 1-7]
参阅全部 CD70 一抗 -
描述
大鼠单克隆抗体[TAN 1-7] to CD70 -
宿主
Rat -
特异性
This antibody is a non-depleting mAb that blocks the CD70-CD27 interaction. -
经测试应用
适用于: ELISA, ICC/IF, Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Recombinant mouse CD70 (extracellular domain, aa residues 41-195).
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阳性对照
- Activated dendritic cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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纯度
Protein A/G purified -
克隆
单克隆 -
克隆编号
TAN 1-7 -
骨髓瘤
NS0 -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab108482于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration.
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Flow Cyt |
Use at an assay dependent concentration.
ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
说明 |
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ELISA
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. -
序列相似性
Belongs to the tumor necrosis factor family. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 21948 Mouse
- SwissProt: O55237 Mouse
- Unigene: 42228 Mouse
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别名
- CD 27L antibody
- CD 70 antibody
- CD27 L antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab108482 被引用在 2 文献中.
- Taraban VY et al. Invariant NKT cells promote CD8+ cytotoxic T cell responses by inducing CD70 expression on dendritic cells. J Immunol 180:4615-20 (2008). PubMed: 18354184
- Rowley TF & Al-Shamkhani A Stimulation by soluble CD70 promotes strong primary and secondary CD8+ cytotoxic T cell responses in vivo. J Immunol 172:6039-46 (2004). PubMed: 15128787