Anti-CD66a + CD66c + CD66d + CD66e抗体[CLB-gran/10] (ab112072)

概述

  • 产品名称Anti-CD66a + CD66c + CD66d + CD66e抗体[CLB-gran/10]
    参阅全部 CD66a + CD66c + CD66d + CD66e 一抗
  • 描述
    小鼠单克隆抗体[CLB-gran/10] to CD66a + CD66c + CD66d + CD66e
  • 特异性ab112072 does not cross-react with normal human peripheral B cells, T cells, monocytes and platelets. Weak reactivity has been observed with malignant cells of patients with B cell-derived CLL.
  • 经测试应用适用于: IHC-P, Flow Cyt, WB, IP, ICCmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human granulocytes

  • 阳性对照
    • Positive tissue: human colon

性能

应用

Our Abpromise guarantee covers the use of ab112072 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 20 µg/ml.
Flow Cyt Use a concentration of 2 - 8 µg/ml. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
WB Use at an assay dependent concentration. Predicted molecular weight: CD66a, 57 kDa; CD66c, 38 kDa; CD66d, 27 kDa; CD66e, 77 kDa.
IP Use at an assay dependent concentration.
ICC Use at an assay dependent concentration.

靶标

  • 功能Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
  • 组织特异性Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
  • 序列相似性Belongs to the immunoglobulin superfamily. CEA family.
    Contains 7 Ig-like (immunoglobulin-like) domains.
  • 翻译后修饰Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Antigen CD66 antibody
    • Biliary glycoprotein antibody
    • Carcinoembryonic antigen antibody
    • Carcinoembryonic antigen related cell adhesion molecule 1 antibody
    • Carcinoembryonic antigen related cell adhesion molecule 3 antibody
    • Carcinoembryonic antigen related cell adhesion molecule 5 antibody
    • Carcinoembryonic antigen related cell adhesion molecule 6 antibody
    • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
    • CD66a antigen antibody
    • CD66d antibody
    • CD66e antibody
    • CD66e antigen antibody
    • CEA antibody
    • CEACAM1 antibody
    • CEACAM3 antibody
    • Ceacam5 antibody
    • CEACAM6 antibody
    • CEAM5_HUMAN antibody
    • Meconium antigen 100 antibody
    see all

Anti-CD66a + CD66c + CD66d + CD66e antibody [CLB-gran/10] (ab112072)参考文献

This product has been referenced in:
  • Teixeira AM  et al. The N-domain of the biliary glycoprotein (BGP) adhesion molecule mediates homotypic binding: domain interactions and epitope analysis of BGPc. Blood 84:211-9 (1994). Read more (PubMed: 7517208) »
  • Tetteroo PA  et al. Neutrophil activation detected by monoclonal antibodies. J Immunol 136:3427-32 (1986). Read more (PubMed: 2937846) »

See all 2 Publications for this product

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