Anti-CD6抗体[MEM-98] (Phycoerythrin) (ab59053)

概述

  • 产品名称
    Anti-CD6抗体[MEM-98] (Phycoerythrin)
    参阅全部 CD6 一抗
  • 描述
    小鼠单克隆抗体[MEM-98] to CD6 (Phycoerythrin)
  • 偶联物
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性
    The antibody reacts with CD6, a 100-130 kD single chain transmembrane glycoprotein expressed on T and B lymphocytes subsets, thymocytes, and acute lymphocytic leukemia cells.
  • 经测试应用
    适用于: IP, WB, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human CD6 antigen purified by immunoaffinity chromatography from HBP ALL cells followed by preparative SDS-PAGE of non boiled non reduced sample (excised piece of gel corresponding to the 100 kDa zone).

  • 常规说明
    Do not use after expiration date stamped on vial label. Short term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.

    The purified antibody was conjugated with R Phycoerythrin (PE) under optimum conditions. The conjugate was purified by size exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

性能

应用

Our Abpromise guarantee covers the use of ab59053 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
WB
Flow Cyt
  • 应用说明
    Flow Cyt: Use 20µl for 106 cells or 100µl whole blood.
    IP: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Use under non reducing conditions. Predicted molecular weight: 100 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Involved in cell adhesion. Binds to CD166.
    • 组织特异性
      Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
    • 序列相似性
      Contains 3 SRCR domains.
    • 翻译后修饰
      After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
      Contains intrachain disulfide bond(s).
    • 细胞定位
      Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD_antigen=CD6 antibody
      • CD6 antibody
      • CD6 antigen Tp120 antibody
      • CD6 molecule antibody
      • CD6_HUMAN antibody
      • FLJ44171 antibody
      • OX52 antibody
      • T cell differentiation antigen CD6 antibody
      • T-cell differentiation antigen CD6 antibody
      • T12 antibody
      • TP120 antibody
      see all

    文献

    ab59053 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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