Anti-CD6抗体[MEM-98] (Phycoerythrin) (ab59053)

概述

  • 产品名称Anti-CD6抗体[MEM-98] (Phycoerythrin)
    参阅全部 CD6 一抗
  • 描述
    小鼠单克隆抗体[MEM-98] to CD6 (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性The antibody reacts with CD6, a 100-130 kD single chain transmembrane glycoprotein expressed on T and B lymphocytes subsets, thymocytes, and acute lymphocytic leukemia cells.
  • 经测试应用适用于: IP, WB, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human CD6 antigen purified by immunoaffinity chromatography from HBP ALL cells followed by preparative SDS-PAGE of non boiled non reduced sample (excised piece of gel corresponding to the 100 kDa zone).

  • 常规说明Do not use after expiration date stamped on vial label. Short term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.

    The purified antibody was conjugated with R Phycoerythrin (PE) under optimum conditions. The conjugate was purified by size exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

性能

应用

Our Abpromise guarantee covers the use of ab59053 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
WB
Flow Cyt
  • 应用说明Flow Cyt: Use 20µl for 106 cells or 100µl whole blood.
    IP: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Use under non reducing conditions. Predicted molecular weight: 100 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Involved in cell adhesion. Binds to CD166.
    • 组织特异性Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
    • 序列相似性Contains 3 SRCR domains.
    • 翻译后修饰After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
      Contains intrachain disulfide bond(s).
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD_antigen=CD6 antibody
      • CD6 antibody
      • CD6 antigen Tp120 antibody
      • CD6 molecule antibody
      • CD6_HUMAN antibody
      • FLJ44171 antibody
      • OX52 antibody
      • T cell differentiation antigen CD6 antibody
      • T-cell differentiation antigen CD6 antibody
      • T12 antibody
      • TP120 antibody
      see all

    Anti-CD6 antibody [MEM-98] (Phycoerythrin) (ab59053)参考文献

    ab59053 has not yet been referenced specifically in any publications.

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