RabMAb

Anti-CD6抗体[EPR4056] (ab109218)

概述

  • 产品名称Anti-CD6抗体[EPR4056]
    参阅全部 CD6 一抗
  • 描述
    兔单克隆抗体[EPR4056] to CD6
  • 经测试应用适用于: WB, IP, IHC-Pmore details
    不适用于: Flow Cyt or ICC
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human CD6.

  • 阳性对照
    • WB: Jurkat, HuT-78, PBMC and Human tonsil lysates IHC-P: Human tonsil and Human lymphocytes infiltrating colon tissues
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab109218 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 90-130 kDa (predicted molecular weight: 72 kDa).
IP 1/10 - 1/100.
IHC-P 1/250 - 1/500. Antigen retrieval is recommended.
  • 应用说明Is unsuitable for Flow Cyt or ICC.
  • 靶标

    • 功能Involved in cell adhesion. Binds to CD166.
    • 组织特异性Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
    • 序列相似性Contains 3 SRCR domains.
    • 翻译后修饰After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
      Contains intrachain disulfide bond(s).
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD_antigen=CD6 antibody
      • CD6 antibody
      • CD6 antigen Tp120 antibody
      • CD6 molecule antibody
      • CD6_HUMAN antibody
      • FLJ44171 antibody
      • OX52 antibody
      • T cell differentiation antigen CD6 antibody
      • T-cell differentiation antigen CD6 antibody
      • T12 antibody
      • TP120 antibody
      see all

    Anti-CD6 antibody [EPR4056] 图像

    • All lanes : Anti-CD6 antibody [EPR4056] (ab109218) at 1/1000 dilution

      Lane 1 : Jurkat lysates
      Lane 2 : HuT-78 lysates
      Lane 3 : PBMC lysates
      Lane 4 : Human tonsil lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 72 kDa
      Observed band size : 90-130 kDa (why is the actual band size different from the predicted?)
    • ab109218, at a 1/100 dilution, staining CD6 in paraffin embedded Human tonsil tissue by Immunohistochemistry.
    • ab109218, at a 1/100 dilution, staining CD6 in paraffin embedded Human lymphocytes infiltrating colon tissue by Immunohistochemistry.
    • ab109218 showing negative staining in Normal kidney tissue.

    • ab109218 showing negative staining in Normal uterus tissue.

    • ab109218 showing negative staining in Normal brain tissue.

    Anti-CD6 antibody [EPR4056] (ab109218)参考文献

    ab109218 has not yet been referenced specifically in any publications.

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