概述

  • 产品名称Anti-CD57抗体[TB01]
    参阅全部 CD57 一抗
  • 描述
    小鼠单克隆抗体[TB01] to CD57
  • 特异性This antibody is specific for CD57.
  • 经测试应用适用于: Flow Cyt, IHC-Fr, IHC-Pmore details
    不适用于: IP or WB
  • 种属反应性
    与反应: Human
  • 免疫原

    Human neuroblastoma cells

  • 阳性对照
    • Human tonsil tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度Ion Exchange Chromatography
  • 克隆单克隆
  • 克隆编号TB01
  • 骨髓瘤P3x63-Ag8.653
  • 同种型IgM
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab33273 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
IHC-Fr
IHC-P
  • 应用说明Flow Cyt: 1/50 - 1/100.
    Use 10µl of the suggested working dilution to label 106 cells in 100µl.

    IHC-Fr: 1/10 - 1/100.
    IHC-P: 1/10 - 1/50.

    This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections but sodium citrate buffer may enhance staining.

    Is unsuitable for IP or WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
    • 组织特异性Mainly expressed in the brain.
    • 通路Protein modification; protein glycosylation.
    • 序列相似性Belongs to the glycosyltransferase 43 family.
    • 细胞定位Golgi apparatus membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 3-glucuronyltransferase 1 antibody
      • 3-glucuronyltransferase antibody
      • B3GA1_HUMAN antibody
      • B3gat1 antibody
      • Beta 1 3 glucuronyltransferase 1 antibody
      • Beta-1 antibody
      • Beta-1,3-glucuronyltransferase 1 antibody
      • CD 57 antibody
      • CD57 antibody
      • CD57 antigen antibody
      • Galactosylgalactosylxylosylprotein 3 beta glucuronosyltransferase 1 antibody
      • Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 antibody
      • GlcAT P antibody
      • GlcAT-P antibody
      • GLCATP antibody
      • GlcUAT P antibody
      • GlcUAT-P antibody
      • GlcUATP antibody
      • Glucuronosyltransferase P antibody
      • HNK 1 antibody
      • HNK1 antibody
      • LEU 7 antibody
      • LEU7 antibody
      • LEU7 antigen antibody
      • NK 1 antibody
      • NK1 antibody
      • UDP GlcUA glycoprotein beta 1 3 glucuronyltransferase antibody
      • UDP-GlcUA:glycoprotein beta-1 antibody
      see all

    Anti-CD57 antibody [TB01] (ab33273)参考文献

    This product has been referenced in:
    • Eriksson M  et al. Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta. J Leukoc Biol 76:667-75 (2004). Read more (PubMed: 15178706) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"