概述
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产品名称Anti-CD55抗体[MEM-118] (Biotin)
参阅全部 CD55 一抗 -
描述小鼠单克隆抗体[MEM-118] to CD55 (Biotin)
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宿主Mouse
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偶联物Biotin
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特异性ab26005 recognises CD55 antigen (Decay accelerating factor).
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经测试应用适用于: Flow Cytmore details
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种属反应性与反应: Human
预测可用于: Non human primates
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免疫原
Tissue/ cell preparation (Human) -T cell line HPB-ALL.
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表位This antibody recognizes an epitope in SCR4 domain of CD55 antigen.
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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存储溶液Preservative: 15mM Sodium Azide
Constituents: PBS, pH 7.4 -
Concentration information loading... -
纯度Purified IgM
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克隆单克隆
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克隆编号MEM-118
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同种型IgM
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研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
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Positive Controls
应用
Our Abpromise guarantee covers the use of ab26005 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
应用说明
Flow Cyt: 1/500 (use indirect immunofluorescence analysis)
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
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组织特异性Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
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序列相似性Belongs to the receptors of complement activation (RCA) family.
Contains 4 Sushi (CCP/SCR) domains. -
结构域The first Sushi domain (SCR1) is not necessary for function. SCR2 and SCR4 provide the proper conformation for the active site on SCR3.
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翻译后修饰The Ser/Thr-rich domain is heavily O-glycosylated.
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细胞定位Cell membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 1604 Human
- Omim: 125240 Human
- SwissProt: P08174 Human
- Unigene: 126517 Human
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别名
- CD 55 antibody
- CD55 antibody
- CD55 antigen antibody
see all
图片
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![Flow Cytometry - Anti-CD55 antibody [MEM-118] (Biotin) (ab26005)](http://www.abcam.cn/ps/products/26/ab26005/Images/ab26005-291034-ab26005FC.jpg)
Flow Cytometry - Anti-CD55 antibody [MEM-118] (Biotin) (ab26005)Surface staining of human peripheral blood cells with anti-CD55 (MEM-118) biotin / streptavidin-APC.
文献
ab26005 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"