Anti-CD55抗体[MEM-118] (Biotin) (ab26005)

概述

  • 产品名称
    Anti-CD55抗体[MEM-118] (Biotin)
    参阅全部 CD55 一抗
  • 描述
    小鼠单克隆抗体[MEM-118] to CD55 (Biotin)
  • 偶联物
    Biotin
  • 特异性
    ab26005 recognises CD55 antigen (Decay accelerating factor).
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
    预测可用于: Non human primates
  • 免疫原

    Tissue/ cell preparation (Human) -T cell line HPB-ALL.

  • 表位
    This antibody recognizes an epitope in SCR4 domain of CD55 antigen.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 15mM Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Purified IgM
  • 克隆
    单克隆
  • 克隆编号
    MEM-118
  • 同种型
    IgM
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab26005 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明
    Flow Cyt: 1/500 (use indirect immunofluorescence analysis)

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
    • 组织特异性
      Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
    • 序列相似性
      Belongs to the receptors of complement activation (RCA) family.
      Contains 4 Sushi (CCP/SCR) domains.
    • 结构域
      The first Sushi domain (SCR1) is not necessary for function. SCR2 and SCR4 provide the proper conformation for the active site on SCR3.
    • 翻译后修饰
      The Ser/Thr-rich domain is heavily O-glycosylated.
    • 细胞定位
      Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD 55 antibody
      • CD55 antibody
      • CD55 antigen antibody
      • CD55 Cromer blood group system antibody
      • CD55 molecule (Cromer blood group) antibody
      • CD55 molecule antibody
      • CD55 molecule, decay accelerating factor for complement (Cromer blood group) antibody
      • Cd55a antibody
      • Complement decay accelerating factor antibody
      • Complement decay-accelerating factor antibody
      • Complement decay-accelerating factor, GPI-anchored antibody
      • CR antibody
      • CROM antibody
      • Cromer Blood Group antigen antibody
      • Cromer blood group system antibody
      • DAF antibody
      • Daf-GPI antibody
      • DAF_HUMAN antibody
      • Daf1 antibody
      • Dcay accelerating factor for complement (CD55, Cromer blood group system) antibody
      • Decay accelarating factor 1, isoform CRA_a antibody
      • Decay accelerating factor (GPI-form) antibody
      • Decay Accelerating Factor for Complement antibody
      • Decay accelerating factor GPI-form antibody
      • Decay accelerating factor soluble-form antibody
      • GPI-DAF antibody
      • TC antibody
      see all

    Anti-CD55 antibody [MEM-118] (Biotin) (ab26005)参考文献

    ab26005 has not yet been referenced specifically in any publications.

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