Anti-CD48抗体[HM48-1] (Phycoerythrin) (ab95608)

概述

  • 产品名称Anti-CD48抗体[HM48-1] (Phycoerythrin)
    参阅全部 CD48 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[HM48-1] to CD48 (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用适用于: ICC/IF, Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse T lymphoma MBL2

  • 阳性对照
    • C57BL/6 splenocytes
  • 常规说明


    HM48-1 is reported to modulate in vitro and in vivo CD48 functions including blocking the CD48/CD2 and CD48/CD244 interactions, inhibiting the proliferative response of mitogen-activated spleen cells, providing a costimulation signal for T cells activated in vitro through their TCR, and prolonging cardiac allograft survival in vivo.

    Excitation: 488 nm Emission: 575 nm.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • Primary antibody说明HM48-1 is reported to modulate in vitro and in vivo CD48 functions including blocking the CD48/CD2 and CD48/CD244 interactions, inhibiting the proliferative response of mitogen-activated spleen cells, providing a costimulation signal for T cells activated in vitro through their TCR, and prolonging cardiac allograft survival in vivo.
  • 克隆单克隆
  • 克隆编号HM48-1
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab95608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration.
Flow Cyt Use 0.06-0.125µg for 105-8 cells. Staining the cell sample in a final volume of 100 µL is recommended.



ab101026-Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
  • 序列相似性Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Antigen CD48 antibody
    • B cell membrane protein antibody
    • B lymphocyte activation marker BLAST 1 antibody
    • B-cell activation marker antibody
    • B-lymphocyte activation marker BLAST-1 antibody
    • BCM 1 surface antigen antibody
    • BCM1 antibody
    • BCM1 surface antigen antibody
    • BLAST 1 antibody
    • BLAST antibody
    • BLAST1 antibody
    • CD 48 antibody
    • CD48 antibody
    • CD48 antigen (B cell membrane protein) antibody
    • CD48 antigen antibody
    • CD48 molecule antibody
    • CD48 protein antibody
    • CD48_HUMAN antibody
    • hCD48 antibody
    • Leucocyte antigen MEM 102 antibody
    • Leukocyte antigen MEM-102 antibody
    • mCD48 antibody
    • MEM 102 antibody
    • MEM-102 antibody
    • MEM102 antibody
    • Signaling lymphocytic activation molecule 2 antibody
    • SLAM family member 2 antibody
    • SLAMF 2 antibody
    • SLAMF2 antibody
    • TCT.1 antibody
    see all

Anti-CD48 antibody [HM48-1] (Phycoerythrin) 图像

  • Immunocytochemistry/ Immunofluorescence analysis of paraformaldehyde fixed Mouse spleen cell labelling CD48 with ab95608 at 1/100 dilution for 10 minutes at 4°C. Nuclei were stained with DAPI.

    See Abreview

  • Staining of C57BL/6 splenocytes with 0.06 µg of Armenian Hamster IgG Isotype Control PE (open histogram) or 0.06 µg of ab95608 (filled histogram). Cells in the lymphocyte gate were used for analysis.

Anti-CD48 antibody [HM48-1] (Phycoerythrin) (ab95608)参考文献

ab95608 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Mouse Cell (spleen)
Specification spleen
Fixative Paraformaldehyde
Permeabilization No
Blocking step Fc-block as blocking agent for 10 minute(s) · Concentration: 1% · Temperature: 4°C
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提交于 May 10 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"