概述

  • 产品名称Anti-CD48抗体[HM48-1]
    参阅全部 CD48 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[HM48-1] to CD48
  • 经测试应用适用于: Flow Cyt, IP, WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse T lymphoma MBL2

  • 阳性对照
    • BALB/c splenocytes
  • 常规说明


    HM48-1 is reported to modulate in vitro and in vivo CD48 functions including blocking the CD48/CD2 and CD48/CD244 interactions, inhibiting the proliferative response of mitogen-activated spleen cells, providing a costimulation signal for T cells activated in vitro through their TCR, and prolonging cardiac allograft survival in vivo.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • Primary antibody说明HM48-1 is reported to modulate in vitro and in vivo CD48 functions including blocking the CD48/CD2 and CD48/CD244 interactions, inhibiting the proliferative response of mitogen-activated spleen cells, providing a costimulation signal for T cells activated in vitro through their TCR, and prolonging cardiac allograft survival in vivo.
  • 克隆单克隆
  • 克隆编号HM48-1
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab95606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.5µg for 105-8 cells. Staining the cell sample in a final volume of 100 µL is recommended.



ab18479-Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 28 kDa.

靶标

  • 功能Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
  • 序列相似性Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Antigen CD48 antibody
    • B cell membrane protein antibody
    • B lymphocyte activation marker BLAST 1 antibody
    • B-cell activation marker antibody
    • B-lymphocyte activation marker BLAST-1 antibody
    • BCM 1 surface antigen antibody
    • BCM1 antibody
    • BCM1 surface antigen antibody
    • BLAST 1 antibody
    • BLAST antibody
    • BLAST1 antibody
    • CD 48 antibody
    • CD48 antibody
    • CD48 antigen (B cell membrane protein) antibody
    • CD48 antigen antibody
    • CD48 molecule antibody
    • CD48 protein antibody
    • CD48_HUMAN antibody
    • hCD48 antibody
    • Leucocyte antigen MEM 102 antibody
    • Leukocyte antigen MEM-102 antibody
    • mCD48 antibody
    • MEM 102 antibody
    • MEM-102 antibody
    • MEM102 antibody
    • Signaling lymphocytic activation molecule 2 antibody
    • SLAM family member 2 antibody
    • SLAMF 2 antibody
    • SLAMF2 antibody
    • TCT.1 antibody
    see all

Anti-CD48 antibody [HM48-1] 图像

  • Staining of BALB/c splenocytes with 0.25 µg of Armenian Hamster IgG Isotype Control Purified (open histogram) or 0.25 µg of ab95606 (filled histogram) followed by Anti-Armenian Hamster IgG FITC. Total viable cells were used for analysis.

Anti-CD48 antibody [HM48-1] (ab95606)参考文献

This product has been referenced in:
  • Möller J  et al. Macrophages lift off surface-bound bacteria using a filopodium-lamellipodium hook-and-shovel mechanism. Sci Rep 3:2884 (2013). Mouse . Read more (PubMed: 24097079) »

See 1 Publication for this product

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