Anti-CD45RC抗体[RP1/12] (Phycoerythrin) (ab90981)

概述

  • 产品名称Anti-CD45RC抗体[RP1/12] (Phycoerythrin)
    参阅全部 CD45RC 一抗
  • 描述
    小鼠单克隆抗体[RP1/12] to CD45RC (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性ab90981 reacts with CD45RC on pre B lymphocytes, B cells, CD8+ T suppressor/cytotoxic cells and a subset of CD4+ T helper (Th) lymphocytes. It weakly reacts with thymocytes.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    PHA stimulated Human lymphocytes.

性能

应用

Our Abpromise guarantee covers the use of ab90981 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 20µl for 106 cells.

靶标

  • 相关性The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species. The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform.
  • 细胞定位Membrane; Single-pass type I membrane protein. Membrane raft. Note: Colocalized with DPP4 in membrane rafts.
  • 数据库链接
  • 别名
    • B220 antibody
    • CD45 antibody
    • CD45R antibody
    • EC 3.1.3.48 antibody
    • GP180 antibody
    • L-CA antibody
    • LCA antibody
    • Leukocyte common antigen antibody
    • loc antibody
    • Ly-5 antibody
    • LY5 antibody
    • Ly5, homolog of antibody
    • Lymphocyte antigen 5 antibody
    • Lyt-4 antibody
    • Protein tyrosine phosphatase receptor type C antibody
    • PTPRC antibody
    • Receptor-type tyrosine-protein phosphatase C antibody
    • RT7 antibody
    • T200 antibody
    • T200 Glycoprotein antibody
    see all

Anti-CD45RC antibody [RP1/12] (Phycoerythrin) (ab90981)参考文献

ab90981 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab90981.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"