Anti-CD45RC抗体[MRC OX-22] (Biotin) (ab33937)

概述

  • 产品名称Anti-CD45RC抗体[MRC OX-22] (Biotin)
    参阅全部 CD45RC 一抗
  • 描述
    小鼠单克隆抗体[MRC OX-22] to CD45RC (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    PHA stimulated rat lymphocytes

  • 阳性对照
    • rat splenocytes.

性能

应用

Our Abpromise guarantee covers the use of ab33937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use neat. Use 10µl of the suggested working dilution to label 106 cells in 100µl.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species. The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform.
    • 细胞定位Membrane; Single-pass type I membrane protein. Membrane raft. Note: Colocalized with DPP4 in membrane rafts.
    • 数据库链接
    • 别名
      • B220 antibody
      • CD45 antibody
      • CD45R antibody
      • EC 3.1.3.48 antibody
      • GP180 antibody
      • L-CA antibody
      • LCA antibody
      • Leukocyte common antigen antibody
      • loc antibody
      • Ly-5 antibody
      • LY5 antibody
      • Ly5, homolog of antibody
      • Lymphocyte antigen 5 antibody
      • Lyt-4 antibody
      • Protein tyrosine phosphatase receptor type C antibody
      • PTPRC antibody
      • Receptor-type tyrosine-protein phosphatase C antibody
      • RT7 antibody
      • T200 antibody
      • T200 Glycoprotein antibody
      see all

    Anti-CD45RC antibody [MRC OX-22] (Biotin) 图像

    • Flow Cytometry analysis of rat splenocytes labeling CD45RC with ab33937.

    Anti-CD45RC antibody [MRC OX-22] (Biotin) (ab33937)参考文献

    ab33937 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us.

    Our labs follow the suggested protocols posted within our Protocol and Troubleshooting Page athttp://www.abcam.com/index.html?pageconfig=popular_protocols. The indirect flow cytometry protocol may be accessed dir...

    Read More

    Thank you for contacting us.

    Optimal dilution for AB33937 from our QC testing is 1:2. We used 10ul of this working dilution to stain one million cells in 100ul total volume (an additional 1:10 dilution). For the streptavidin detection reagen...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"