概述
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产品名称Anti-CD45RC抗体[MIL15]
参阅全部 CD45RC 一抗 -
描述小鼠单克隆抗体[MIL15] to CD45RC
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宿主Mouse
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经测试应用适用于: IHC-Fr, IHC-P, Flow Cytmore details
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种属反应性与反应: Pig
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免疫原
Full length native protein (purified) (Pig). (Cells isolated from porcine mesenteric lymph node).
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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存储溶液Preservative: 0.09% Sodium Azide
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纯度Tissue culture supernatant
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克隆单克隆
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克隆编号MIL15
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同种型IgM
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab14125 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-Fr | ||
| IHC-P | ||
| Flow Cyt |
应用说明
FACS: Use 10µl for 106 cells.
IHC-P: Use at an assay dependent dilution.
IHC-Fr: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
IHC-P: Use at an assay dependent dilution.
IHC-Fr: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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相关性The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species. The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform.
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细胞定位Membrane; Single-pass type I membrane protein. Membrane raft. Note: Colocalized with DPP4 in membrane rafts.
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别名
- B220 antibody
- CD45 antibody
- CD45R antibody
see all
文献
ab14125 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"