Anti-CD45.1抗体[NDS 58] (FITC) (ab33925)

概述

  • 产品名称Anti-CD45.1抗体[NDS 58] (FITC)
    参阅全部 CD45.1 一抗
  • 描述
    大鼠单克隆抗体[NDS 58] to CD45.1 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性MCA415F recognises rat CD45.1 (RT7.1), expressed by rat strains including AO, BN, DA, LEW and PVG. The antibody does not react with the RT7.2 alloantigen.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Thymocytes from LEW rat.

  • 阳性对照
    • Spleen cells

性能

应用

Our Abpromise guarantee covers the use of ab33925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Neat - 1/5.
    Use 10µl of the suggested working dilution to label 106 cells in 100µl.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性CD45 is an essential regulator of leukocyte activation and development, and is now known to be a protein tyrosine phosphatase, e.g. CD45 is able to dephosphorylate the Src family of protein kinases. This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants and as allelic forms CD45.1/Ly5.1 and CD45.2/Ly5.2. The former arises as a result of alternative splicing of different exons. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies in which resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation.
    • 细胞定位Type I membrane protein.
    • 数据库链接
    • 别名
      • B220 antibody
      • CD45 antibody
      • CD45 antigen antibody
      • CD45R antibody
      • GP180 antibody
      • L-CA antibody
      • LCA antibody
      • LY5 antibody
      • Protein tyrosine phosphatase receptor type C antibody
      • Protein tyrosine phosphatase, receptor type, c polypeptide antibody
      • Receptor type tyrosine protein phosphatase C antibody
      • T200 antibody
      • T200 glycoprotein antibody
      • T200 leukocyte common antigen antibody
      see all

    Anti-CD45.1 antibody [NDS 58] (FITC) 图像

    • Staining of rat spleen cells with rat anti-rat CD45.1 (FITC) antibody (ab33925).

    Anti-CD45.1 antibody [NDS 58] (FITC) (ab33925)参考文献

    ab33925 has not yet been referenced specifically in any publications.

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