概述

  • 产品名称Anti-CD44v3抗体[VFF-327]
  • 描述
    小鼠单克隆抗体[VFF-327] to CD44v3
  • 特异性This antibody specifically recognises an epitope encoded by exon V3 on the variant portion of human CD44
  • 经测试应用适用于: Flow Cyt, IHC-Fr, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    The details of the immunogen for this antibody are not available.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度IgG fraction
  • 克隆单克隆
  • 克隆编号VFF-327
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab34229 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
IHC-Fr
IHC-P
  • 应用说明Flow Cyt: Use 10µl (at a concentration of 10 µg/ml) for 106 cells in 100µl.
    IHC-Fr: Use at a concentration of 10 µg/ml.
    IHC-P: Use at a concentration of 10 µg/ml. Antigen retrieval using heat treatment prior to staining of paraffin sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. There are 17 different isoforms.
    • 细胞定位Membrane; single-pass type I membrane protein
    • 数据库链接
    • 别名
      • CD44 antigen antibody
      • CD44 molecule antibody
      • Heparan sulfate proteoglycan antibody
      • IN antibody
      • MUTCH 1 antibody
      • Phagocytic glycoprotein I antibody
      see all

    Anti-CD44v3 antibody [VFF-327] (ab34229)参考文献

    This product has been referenced in:
    • Alam TN  et al. Differential expression of CD44 during human prostate epithelial cell differentiation. J Histochem Cytochem 52:1083-90 (2004). Read more (PubMed: 15258184) »
    • Seiter S  et al. Mitigation of delayed-type hypersensitivity reactions by a CD44 variant isoform v3-specific antibody: blockade of leukocyte egress. J Invest Dermatol 113:11-21 (1999). Read more (PubMed: 10417612) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"