概述

  • 产品名称Anti-CD43抗体[MT1]
    参阅全部 CD43 一抗
  • 描述
    小鼠单克隆抗体[MT1] to CD43
  • 经测试应用适用于: WB, IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human lymphocytes.

  • 阳性对照
    • Human mantle cell lymphoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab89691 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
IHC-Fr
  • 应用说明IHC-P: 1/20 - 1/40.
    Trypsin digestion of paraffin sections may enhance staining in some cases. 60 minutes primary antibody incubation at 25oC. Standard ABC technique.
    IHC-Fr: 1/20 - 1/40.
    WB: 1/250 - 1/400. Predicted molecular weight: 40 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
    • 组织特异性Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
    • 翻译后修饰Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD 43 antibody
      • CD43 antibody
      • CD43 antigen antibody
      • Galactoglycoprotein antibody
      • GALGP antibody
      • GPL 115 antibody
      • GPL115 antibody
      • Human gene for sialophorin antibody
      • Leucocyte sialoglycoprotein antibody
      • LEUK_HUMAN antibody
      • Leukocyte large sialoglycoprotein antibody
      • Leukocyte sialoglycoprotein antibody
      • Leukosialin antibody
      • LSN antibody
      • Ly-48 antibody
      • sialophorin (gpL115, leukosialin, CD43) antibody
      • Sialophorin antibody
      • Spn antibody
      see all

    Anti-CD43 antibody [MT1] 图像

    • ab89691 at 1/20 dilution staining CD43 in Human mantle cell lymphoma by Immunohistochemistry, Paraffin-embedded tissue. Note intense membrane staining of tumor cells

    Anti-CD43 antibody [MT1] (ab89691)参考文献

    This product has been referenced in:
    • Guye P  et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun 7:10243 (2016). IF ; Human . Read more (PubMed: 26732624) »
    • Xiao LI  et al. Multiple myeloma-associated skin light chain amyloidosis: A case of misdiagnosis. Oncol Lett 11:3617-3620 (2016). IHC ; Human . Read more (PubMed: 27284363) »

    See all 2 Publications for this product

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