Anti-CD43抗体[MEM-59] (Phycoerythrin) (ab60903)

概述

  • 产品名称Anti-CD43抗体[MEM-59] (Phycoerythrin)
    参阅全部 CD43 一抗
  • 描述
    小鼠单克隆抗体[MEM-59] to CD43 (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性ab60903 recognizes neuraminidase-sensitive epitope on CD43 (Leukosialin).
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human T lymphocytes.

  • 阳性对照
    • Human blood cells
  • 常规说明Avoid prolonged exposure to light. Short-term exposure to room temperature should not affect the quality of the reagent.

性能

应用

Our Abpromise guarantee covers the use of ab60903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use 20µl per 100µl of whole blood or 106 cells.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
    • 组织特异性Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
    • 翻译后修饰Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD 43 antibody
      • CD43 antibody
      • CD43 antigen antibody
      • Galactoglycoprotein antibody
      • GALGP antibody
      • GPL 115 antibody
      • GPL115 antibody
      • Human gene for sialophorin antibody
      • Leucocyte sialoglycoprotein antibody
      • LEUK_HUMAN antibody
      • Leukocyte large sialoglycoprotein antibody
      • Leukocyte sialoglycoprotein antibody
      • Leukosialin antibody
      • LSN antibody
      • Ly-48 antibody
      • sialophorin (gpL115, leukosialin, CD43) antibody
      • Sialophorin antibody
      • Spn antibody
      see all

    Anti-CD43 antibody [MEM-59] (Phycoerythrin) (ab60903)参考文献

    ab60903 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. This antibody belongs to the CD43 antibodies of epitope cluster A, which are able to inhibit the binding of biotinylated WDS 1.C1 by more than 90%, induce strong homotypic aggregation and recognize a neuraminidase-sensiti...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"