Anti-CD43抗体[DF-T1], prediluted (ab964)


  • 产品名称Anti-CD43抗体[DF-T1], prediluted
    参阅全部 CD43 一抗
  • 描述
    小鼠单克隆抗体[DF-T1] to CD43, prediluted
  • 特异性It recognizes a 95/115/135kDa (dependent upon the extent of glycosylation) cell surface glycoprotein, identified as CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein. CD43 is expressed on all thymocytes and T-cells. This antibody is useful for identification and classification of T-cell malignancies and low grade B-cell lymphoma.
  • 经测试应用适用于: IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Myeloblastic KG1 cells

  • 阳性对照
    • T-cell lymphoma or tonsil.


Our Abpromise guarantee covers the use of ab964 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
  • 应用说明This antibody is ready to use.
    Heat mediated antigen retrieval can be used.
    However, for optimum fixation, tissues should be fixed in either B-5 or an alcohol-based fixation, in which case no pretreatment is necessary.
    In most cases using optimal fixation, dilution of the primary antibody can be increased 2-4 fold.
    We recommend incubating sections with the antibody for 30-60 minutes at room temperature.
  • 靶标

    • 功能One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
    • 组织特异性Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
    • 翻译后修饰Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD 43 antibody
      • CD43 antibody
      • CD43 antigen antibody
      • Galactoglycoprotein antibody
      • GALGP antibody
      • GPL 115 antibody
      • GPL115 antibody
      • Human gene for sialophorin antibody
      • Leucocyte sialoglycoprotein antibody
      • LEUK_HUMAN antibody
      • Leukocyte large sialoglycoprotein antibody
      • Leukocyte sialoglycoprotein antibody
      • Leukosialin antibody
      • LSN antibody
      • Ly-48 antibody
      • sialophorin (gpL115, leukosialin, CD43) antibody
      • Sialophorin antibody
      • Spn antibody
      see all

    Anti-CD43 antibody [DF-T1], prediluted (ab964)参考文献

    This product has been referenced in:
    • de Smet W  et al. A new CD43 monoclonal antibody induces homotypic aggregation of human leucocytes through a CD11a/CD18-dependent and -independent mechanism. Immunology 79:46-54 (1993). Read more (PubMed: 8099567) »
    • Petruch UR  et al. Frequent expression of haemopoietic and non-haemopoietic antigens by neoplastic plasma cells: an immunohistochemical study using formalin-fixed, paraffin-embedded tissue. Histopathology 20:35-40 (1992). Read more (PubMed: 1737624) »

    See all 3 Publications for this product

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