Anti-CD43抗体[DF-T1] (FITC) (ab82431)

概述

  • 产品名称Anti-CD43抗体[DF-T1] (FITC)
    参阅全部 CD43 一抗
  • 描述
    小鼠单克隆抗体[DF-T1] to CD43 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性Human CD43
  • 经测试应用适用于: IHC-Fr, Flow Cyt, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    The details of the immunogen for this antibody are not available

性能

应用

Our Abpromise guarantee covers the use of ab82431 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.
Flow Cyt Use 5µl for 106 cells. ab91356-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
  • 组织特异性Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
  • 翻译后修饰Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 43 antibody
    • CD43 antibody
    • CD43 antigen antibody
    • Galactoglycoprotein antibody
    • GALGP antibody
    • GPL 115 antibody
    • GPL115 antibody
    • Human gene for sialophorin antibody
    • Leucocyte sialoglycoprotein antibody
    • LEUK_HUMAN antibody
    • Leukocyte large sialoglycoprotein antibody
    • Leukocyte sialoglycoprotein antibody
    • Leukosialin antibody
    • LSN antibody
    • Ly-48 antibody
    • sialophorin (gpL115, leukosialin, CD43) antibody
    • Sialophorin antibody
    • Spn antibody
    see all

Anti-CD43 antibody [DF-T1] (FITC) 图像

  • Overlay histogram showing peripheral blood lymphocytes stained with ab82431 (red line). The cells incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab82431, 0.5 µg/1x106 cells) for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 FITC (2 µg/1x106 cells ) for 30 min at 22°C. Acquisition of >5,000 events was performed.

Anti-CD43 antibody [DF-T1] (FITC) (ab82431)参考文献

ab82431 has not yet been referenced specifically in any publications.

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