Anti-CD42a抗体[GR-P] (CF405M) (ab119483)

概述

  • 产品名称Anti-CD42a抗体[GR-P] (CF405M)
    参阅全部 CD42a 一抗
  • 描述
    小鼠单克隆抗体[GR-P] to CD42a (CF405M)
  • 偶联物CF405M. Ex: 408nm, Em: 452nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human red blood cells and platelets.

  • 阳性对照
    • Human platelets in normal peripheral blood.
  • 常规说明

    CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液pH: 7.20
    Preservative: 0.09% Sodium azide
    Note: Buffer containing antibody stabilizer solution.
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆单克隆
  • 克隆编号GR-P
  • 同种型IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab119483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 5µl for 106 cells. ab126036-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 功能The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
  • 疾病相关Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
  • 序列相似性Contains 1 LRR (leucine-rich) repeat.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD42a antibody
    • Glycoprotein 9 antibody
    • Glycoprotein IX antibody
    • Glycoprotein IX (platelet) antibody
    • Glycoprotein IX precursor antibody
    • GP IX antibody
    • GP-IX antibody
    • GP9 antibody
    • GPIX antibody
    • GPIX_HUMAN antibody
    • Platelet glycoprotein IX antibody
    see all

Anti-CD42a antibody [GR-P] (CF405M) 图像

  • ab119483, at 5 µl/106 cells, staining CD42a in Human platelets from normal Human peripheral blood cells by Flow Cytometry. Total events were used for the analysis.

Anti-CD42a antibody [GR-P] (CF405M) (ab119483)参考文献

ab119483 has not yet been referenced specifically in any publications.

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