Anti-CD40 (phospho T254)抗体(ab79278)

概述

  • 产品名称Anti-CD40 (phospho T254)抗体
    参阅全部 CD40 一抗
  • 描述
    兔多克隆抗体to CD40 (phospho T254)
  • 特异性ab79278 detects endogenous levels of CD40 only when phosphorylated at threonine 254 (Human: Thr254; Mouse: Thr255).
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic phosphopeptide derived from human CD40 around the phosphorylation site of threonine 254 (Q-E-TP-L-H).

  • 阳性对照
    • COLO cell extracts, treated with Insulin (0.01U/ml, 15mins).

性能

应用

Our Abpromise guarantee covers the use of ab79278 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 31 kDa.
ELISA 1/5000.

靶标

  • 功能Receptor for TNFSF5/CD40LG.
  • 组织特异性B-cells and in primary carcinomas.
  • 疾病相关Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
  • 序列相似性Contains 4 TNFR-Cys repeats.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI326936 antibody
    • B cell associated molecule CD40 antibody
    • B cell surface antigen CD40 antibody
    • B cell-associated molecule antibody
    • B-cell surface antigen CD40 antibody
    • Bp50 antibody
    • CD 40 antibody
    • CD40 antibody
    • CD40 antigen (TNF receptor superfamily member 5) antibody
    • CD40 antigen antibody
    • CD40 molecule antibody
    • CD40 molecule, TNF receptor superfamily member 5 antibody
    • CD40 protein antibody
    • CD40 type II isoform antibody
    • CD40L receptor antibody
    • CDw40 antibody
    • GP39 antibody
    • HIGM1 antibody
    • IGM antibody
    • IMD3 antibody
    • MGC9013 antibody
    • Nerve growth factor receptor related B lymphocyte activation molecule antibody
    • OTTHUMP00000031699 antibody
    • OTTHUMP00000031700 antibody
    • p50 antibody
    • T-BAM antibody
    • TBAM antibody
    • TNF receptor superfamily member 5 antibody
    • TNFRSF5 antibody
    • TNR5_HUMAN antibody
    • TRAP antibody
    • Tumor necrosis factor receptor superfamily , member 5 antibody
    • Tumor necrosis factor receptor superfamily member 5 antibody
    • Tumor necrosis factor receptor superfamily member 5 precursor antibody
    • Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody
    see all

Anti-CD40 (phospho T254) antibody 图像

  • All lanes : Anti-CD40 (phospho T254) antibody (ab79278) at 1/500 dilution

    Lane 1 : COLO cell extract, treated with Insulin (0.01U/ml, 15mins)
    Lane 2 : COLO cell extract, treated with Insulin (0.01U/ml, 15mins) with immunising phosphopeptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 31 kDa
    Observed band size : 26 kDa (why is the actual band size different from the predicted?)

Anti-CD40 (phospho T254) antibody (ab79278)参考文献

ab79278 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab79278.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"