概述

  • 产品名称Anti-CD40抗体[HM40-3] (FITC)
    参阅全部 CD40 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[HM40-3] to CD40 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    (BALB/c x NZB) F1 mouse-derived lymphoma WEHI-231 cells.

  • 阳性对照
    • Mouse BALB/c splenocytes

性能

应用

Our Abpromise guarantee covers the use of ab95535 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.5-1µg for 105-8 cells. Staining the cell sample in a final volume of 100µl is recommended.

靶标

  • 功能Receptor for TNFSF5/CD40LG.
  • 组织特异性B-cells and in primary carcinomas.
  • 疾病相关Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
  • 序列相似性Contains 4 TNFR-Cys repeats.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI326936 antibody
    • B cell associated molecule CD40 antibody
    • B cell surface antigen CD40 antibody
    • B cell-associated molecule antibody
    • B-cell surface antigen CD40 antibody
    • Bp50 antibody
    • CD 40 antibody
    • CD40 antibody
    • CD40 antigen (TNF receptor superfamily member 5) antibody
    • CD40 antigen antibody
    • CD40 molecule antibody
    • CD40 molecule, TNF receptor superfamily member 5 antibody
    • CD40 protein antibody
    • CD40 type II isoform antibody
    • CD40L receptor antibody
    • CDw40 antibody
    • GP39 antibody
    • HIGM1 antibody
    • IGM antibody
    • IMD3 antibody
    • MGC9013 antibody
    • Nerve growth factor receptor related B lymphocyte activation molecule antibody
    • OTTHUMP00000031699 antibody
    • OTTHUMP00000031700 antibody
    • p50 antibody
    • T-BAM antibody
    • TBAM antibody
    • TNF receptor superfamily member 5 antibody
    • TNFRSF5 antibody
    • TNR5_HUMAN antibody
    • TRAP antibody
    • Tumor necrosis factor receptor superfamily , member 5 antibody
    • Tumor necrosis factor receptor superfamily member 5 antibody
    • Tumor necrosis factor receptor superfamily member 5 precursor antibody
    • Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody
    see all

Anti-CD40 antibody [HM40-3] (FITC) 图像

  • Flow cytometry staining of BALB/c splenocytes with 0.5 µg of Armenian Hamster IgG Isotype Control FITC (open histogram) or 0.5 µg of ab95535 (filled histogram). Total viable cells were used for analysis.

Anti-CD40 antibody [HM40-3] (FITC) (ab95535)参考文献

This product has been referenced in:
  • Ripoll È  et al. CD40 gene silencing reduces the progression of experimental lupus nephritis modulating local milieu and systemic mechanisms. PLoS One 8:e65068 (2013). Read more (PubMed: 23799000) »
  • Inaba K  et al. The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. J Exp Med 180:1849-60 (1994). Read more (PubMed: 7525841) »

See all 2 Publications for this product

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