概述
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产品名称Anti-CD40抗体[HI40a] (CF405M)
参阅全部 CD40 一抗 -
描述小鼠单克隆抗体[HI40a] to CD40 (CF405M)
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宿主Mouse
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偶联物CF405M. Ex: 408nm, Em: 452nm
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经测试应用适用于: Flow Cytmore details
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种属反应性与反应: Human
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免疫原
Tonsil cells.
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阳性对照
- Normal Human peripheral blood cells.
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常规说明
CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at +4°C.
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存储溶液pH: 7.20
Preservative: 0.09% Sodium azide
Note: Buffer containing antibody stabilizer solution. -
Concentration information loading... -
纯度Immunogen affinity purified
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克隆单克隆
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克隆编号HI40a
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同种型IgG1
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研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab119494 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt | Use 5µl for 106 cells. ab126026 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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靶标
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功能Receptor for TNFSF5/CD40LG.
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组织特异性B-cells and in primary carcinomas.
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疾病相关Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
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序列相似性Contains 4 TNFR-Cys repeats.
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细胞定位Secreted and Cell membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 958 Human
- Omim: 109535 Human
- SwissProt: P25942 Human
- Unigene: 472860 Human
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别名
- AI326936 antibody
- B cell associated molecule CD40 antibody
- B cell surface antigen CD40 antibody
see all
图片
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![Flow Cytometry - Anti-CD40 antibody [HI40a] (CF405M) (ab119494)](http://www.abcam.cn/ps/datasheet/images/119/ab119494/CD40-Primary-antibodies-ab119494-1.jpg)
Flow Cytometry - Anti-CD40 antibody [HI40a] (CF405M) (ab119494)ab119494, at 5 µl/106 cells, staining CD40 in normal Human peripheral blood cells by Flow Cytometry. Cells in the lymphocyte gate were used for the analysis.
文献
ab119494 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"