Anti-CD40抗体[HI40a] (CF405M) (ab119494)

概述

• 产品名称Anti-CD40抗体[HI40a] (CF405M)
  参阅全部 CD40 一抗
• 描述
  小鼠单克隆抗体[HI40a] to CD40 (CF405M)
• 偶联物CF405M. Ex: 408nm, Em: 452nm
• 经测试应用适用于: Flow Cytmore details
• 种属反应性
  与反应: Human
  
• 免疫原

  Tonsil cells.

• 阳性对照
  • Normal Human peripheral blood cells.
• 常规说明

  CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye^®, BD Horizon™ V450.

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Store at +4°C.
• 存储溶液pH: 7.20
  Preservative: 0.09% Sodium azide
  Note: Buffer containing antibody stabilizer solution.
• Concentration information loading...
• 纯度Immunogen affinity purified
• 克隆单克隆
• 克隆编号HI40a
• 同种型IgG1
• 研究领域
  • Immunology
  • Adaptive Immunity
  • B Cells
  • CD

  • Cardiovascular
  • Atherosclerosis
  • Vascular Inflammation
  • Innate and adaptive immunity

  • Stem Cells
  • Hematopoietic Progenitors
  • Lymphoid
  • B Lymphocytic Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Myeloid
  • Dendritic Cell Lineage

相关产品

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

应用

靶标

• 功能Receptor for TNFSF5/CD40LG.
• 组织特异性B-cells and in primary carcinomas.
• 疾病相关Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
• 序列相似性Contains 4 TNFR-Cys repeats.
• 细胞定位Secreted and Cell membrane.

• Target information above from: UniProt accession P25942 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 958 Human
  • Omim: 109535 Human
  • SwissProt: P25942 Human
  • Unigene: 472860 Human
• 别名
  • AI326936 antibody
  • B cell associated molecule CD40 antibody
  • B cell surface antigen CD40 antibody

  • B cell-associated molecule antibody
  • B-cell surface antigen CD40 antibody
  • Bp50 antibody
  • CD 40 antibody
  • CD40 antibody
  • CD40 antigen (TNF receptor superfamily member 5) antibody
  • CD40 antigen antibody
  • CD40 molecule antibody
  • CD40 molecule, TNF receptor superfamily member 5 antibody
  • CD40 protein antibody
  • CD40 type II isoform antibody
  • CD40L receptor antibody
  • CDw40 antibody
  • GP39 antibody
  • HIGM1 antibody
  • IGM antibody
  • IMD3 antibody
  • MGC9013 antibody
  • Nerve growth factor receptor related B lymphocyte activation molecule antibody
  • OTTHUMP00000031699 antibody
  • OTTHUMP00000031700 antibody
  • p50 antibody
  • T-BAM antibody
  • TBAM antibody
  • TNF receptor superfamily member 5 antibody
  • TNFRSF5 antibody
  • TNR5_HUMAN antibody
  • TRAP antibody
  • Tumor necrosis factor receptor superfamily , member 5 antibody
  • Tumor necrosis factor receptor superfamily member 5 antibody
  • Tumor necrosis factor receptor superfamily member 5 precursor antibody
  • Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody

  see all