Anti-CD40抗体[3/23] (FITC) (ab22470)


  • 产品名称
    Anti-CD40抗体[3/23] (FITC)
    参阅全部 CD40 一抗
  • 描述
    大鼠单克隆抗体[3/23] to CD40 (FITC)
  • 偶联物
    FITC. Ex: 493nm, Em: 528nm
  • 特异性
    Specificity was checked by ELISA and flow cytometry using BHK cells transfected with mouse CD40. It does not react with normal mouse Ig or with human Ig1 and will stain most mature mouse B cells. It dos not cross react with mouse T cells. Clone 3/23 is a powerful activator of normal B cells especially in the prescence of IL4.
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Fusion protein corresponding to Human CD40. Extracellular domain of mouse CD40 and the Fc portion of human IgG1



Our Abpromise guarantee covers the use of ab22470 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明
    Flow Cyt: Use 10ul of the suggested working dilution to label 10E6 cells in 100ul.

    Use at an assay dependent dilution.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Receptor for TNFSF5/CD40LG.
    • 组织特异性
      B-cells and in primary carcinomas.
    • 疾病相关
      Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
    • 序列相似性
      Contains 4 TNFR-Cys repeats.
    • 细胞定位
      Secreted and Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AI326936 antibody
      • B cell associated molecule CD40 antibody
      • B cell surface antigen CD40 antibody
      • B cell-associated molecule antibody
      • B-cell surface antigen CD40 antibody
      • Bp50 antibody
      • CD 40 antibody
      • CD40 antibody
      • CD40 antigen (TNF receptor superfamily member 5) antibody
      • CD40 antigen antibody
      • CD40 molecule antibody
      • CD40 molecule, TNF receptor superfamily member 5 antibody
      • CD40 protein antibody
      • CD40 type II isoform antibody
      • CD40L receptor antibody
      • CDw40 antibody
      • GP39 antibody
      • HIGM1 antibody
      • IGM antibody
      • IMD3 antibody
      • MGC9013 antibody
      • Nerve growth factor receptor related B lymphocyte activation molecule antibody
      • OTTHUMP00000031699 antibody
      • OTTHUMP00000031700 antibody
      • p50 antibody
      • T-BAM antibody
      • TBAM antibody
      • TNF receptor superfamily member 5 antibody
      • TNFRSF5 antibody
      • TNR5_HUMAN antibody
      • TRAP antibody
      • Tumor necrosis factor receptor superfamily , member 5 antibody
      • Tumor necrosis factor receptor superfamily member 5 antibody
      • Tumor necrosis factor receptor superfamily member 5 precursor antibody
      • Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody
      see all

    Anti-CD40 antibody [3/23] (FITC) 图像

    • ab22740 staining CD40 in mouse spleen cells by Flow Cytometric analysis.

    Anti-CD40 antibody [3/23] (FITC) (ab22470)参考文献

    ab22470 has not yet been referenced specifically in any publications.

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