Anti-CD4 + CD8抗体[EDU-2 + 733] (Dual color: FITC + PE) (ab1232)

概述

  • 产品名称Anti-CD4 + CD8抗体[EDU-2 + 733] (Dual color: FITC + PE)
    参阅全部 CD4 + CD8 一抗
  • 描述
    小鼠单克隆抗体[EDU-2 + 733] to CD4 + CD8 (Dual color: FITC + PE)
  • 偶联物Dual color: FITC + PE
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 常规说明This product is a mixture of two clones: CD4 = Clone:EDU-2, Isotype:IgG2a, Label:FITC CD8 = Clone:733, Isotype:IgG1, Label:PE This product contains sodium azide, which under acid conditions yields hydrazoic acid, a toxic compound. Azide compounds should be diluted with running water before being discarded to avoid deposits in lead or copper plumbing where explosive conditions may develop.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液PBS with 0.5% BSA and 0.1% sodium azide
  • Concentration information loading...
  • 克隆单克隆
  • 克隆编号EDU-2 + 733
  • 骨髓瘤unknown
  • 轻链类型unknown
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab1232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Percentage count of T helper/inducer lymphocytes (CD4+) in human lysed whole peripheral blood or mononuclear cells separated by density gradient.
    Percentage count of T suppressor/cytotoxic lymphocytes (CD8+).
    Control autoimmune pathologies, immunodeficiencies and immunosuppressivetherapies.
    Studies of HIV (Human Immunodeficiency Virus) infection.

    CD4(FITC) / CD8 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.

    10µl ofCD4(FITC) / CD8 (PE) is sufficient for labelling 1x106 cells.
  • 靶标

    • 相关性CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
    • 细胞定位Membrane; single pass type I membrane protein.
    • 数据库链接
    • 别名
      • CD4 antigen antibody
      • CD4 molecule antibody
      • CD4 mut antibody
      • CD4 receptor antibody
      • CD8 antigen alpha polypeptide antibody
      • CD8A antibody
      • CD8a antigen antibody
      • CD8a molecule antibody
      • CD8B antibody
      • CD8b antigen antibody
      • CD8b molecule antibody
      • CD8B1 antibody
      • MAL antibody
      • p37 antibody
      • p55 antibody
      • T cell antigen Leu2 antibody
      • T cell surface glycoprotein CD4 antibody
      • T8 T cell antigen antibody
      see all

    Anti-CD4 + CD8 antibody [EDU-2 + 733] (Dual color: FITC + PE) (ab1232)参考文献

    ab1232 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"