存放说明 Shipped at 4°C. Store at +4°C.
存储溶液 Preservative: 0.09% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
Primary antibody说明 This antibody inhibits proliferation and IL2 production in the MLR reaction.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1 - 1/10.
Use 10µl of the suggested working dilution to label 10
6 cells in 100µl. ab91357-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
功能 Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
序列相似性 Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain.
翻译后修饰 Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.
细胞定位 Cell membrane. Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
Information by UniProt
CD 4 antibody
CD4 (L3T4) antibody
Anti-CD4 antibody [W3/25] (Phycoerythrin) (ab33783)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"