Anti-CD4抗体[SP35], prediluted (ab101530)


  • 产品名称Anti-CD4抗体[SP35], prediluted
    参阅全部 CD4 一抗
  • 描述
    兔单克隆抗体[SP35] to CD4, prediluted
  • 经测试应用适用于: Flow Cyt, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Pig
  • 免疫原

    A synthetic peptide corresponding to internal region of Human CD4.

  • 阳性对照
    • Human Tonsil, Human T cell lymphoma



Our Abpromise guarantee covers the use of ab101530 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
IHC-P Use at an assay dependent concentration.

Antigen retrieval is recommended: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.


  • 功能Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
  • 序列相似性Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 翻译后修饰Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.
  • 细胞定位Cell membrane. Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 4 antibody
    • CD4 (L3T4) antibody
    • CD4 antibody
    • CD4 antigen (p55) antibody
    • CD4 antigen antibody
    • CD4 molecule antibody
    • CD4 receptor antibody
    • CD4+ Lymphocyte deficiency, included antibody
    • CD4_HUMAN antibody
    • CD4mut antibody
    • L3T4 antibody
    • Leu3 antibody
    • Ly-4 antibody
    • Lymphocyte antigen CD4 antibody
    • MGC165891 antibody
    • OTTHUMP00000238897 antibody
    • p55 antibody
    • T cell antigen T4 antibody
    • T cell antigen T4/LEU3 antibody
    • T cell differentiation antigen L3T4 antibody
    • T cell OKT4 deficiency, included antibody
    • T cell surface antigen T4/Leu 3 antibody
    • T cell surface antigen T4/Leu3 antibody
    • T cell surface glycoprotein CD4 antibody
    • T-cell surface antigen T4/Leu-3 antibody
    • T-cell surface glycoprotein CD4 antibody
    • W3/25 antibody
    • W3/25 antigen antibody
    see all

Anti-CD4 antibody [SP35], prediluted 图像

  • Flow cytometric analysis of rabbit anti-CD4 (SP35) antibody, prediluted, ab101530 in Jurkats cells (green) compared to negative control of rabbit IgG (blue)

  • Staining of Human CD4 in a Formalin/PFA-fixed paraffin-embedded section of Human T cell lymphoma using ab101530 at a dilution of 1/1.

Anti-CD4 antibody [SP35], prediluted (ab101530)参考文献

ab101530 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Frozen sections)
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 40% · Temperature: 20°C
Sample Human Tissue sections (human tonsil)
Specification human tonsil
Permeabilization Yes - saponin
Fixative Paraformaldehyde

Mr. jan misiak

Verified customer

提交于 May 13 2014

Thank you for your enquiry.

I have checked these product numbers. I am sorry to confirm that ab4098 is discontinued and apologize for the inconvenience.

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