产品名称 Anti-CD4抗体[CD4-D2] 参阅全部 CD4 一抗
大鼠单克隆抗体[CD4-D2] to CD4
Flow Cyt more details
Purified CD4+ mouse LN cells.
存放说明 Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液 Preservative: None
Concentration information loading...
纯度 Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明 Flow Cyt: 1/1. Add 5µl per 10 6 cells.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能 Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
序列相似性 Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain.
翻译后修饰 Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.
细胞定位 Cell membrane. Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
Information by UniProt
CD 4 antibody
CD4 (L3T4) antibody
Anti-CD4 antibody [CD4-D2] (ab40967)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"