概述

  • 产品名称Anti-CD38抗体[FS02] (FITC)
    参阅全部 CD38 一抗
  • 描述
    小鼠单克隆抗体[FS02] to CD38 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性This antibody reacts with a type II membrane glycopeptide with a transmembrane sequence near the NH2-terminus.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human

应用

Our Abpromise guarantee covers the use of ab1173 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明HIV Syndromes and other clinical situations characterized by lymphocyte in vivoactivation in human lysed whole peripheral blood or mononuclear cells separated by density gradient.

    CD38 (FITC) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.

    10µl ofCD38 (FITC) is sufficient for labelling of 1x106 cells.
  • 靶标

    • 功能Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
    • 组织特异性Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
    • 序列相似性Belongs to the ADP-ribosyl cyclase family.
    • 发展阶段Preferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 形式There are 2 isoforms produced by alternative splicing.
    • 别名
      • Acute lymphoblastic leukemia cells antigen CD38 antibody
      • ADP ribosyl cyclase 1 antibody
      • ADP ribosyl cyclase antibody
      • ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody
      • ADP-ribosyl cyclase 1 antibody
      • ADPRC 1 antibody
      • ADPRC1 antibody
      • cADPr hydrolase 1 antibody
      • CD 38 antibody
      • CD38 antibody
      • CD38 antigen (p45) antibody
      • CD38 antigen antibody
      • CD38 molecule antibody
      • Cd38-rs1 antibody
      • CD38_HUMAN antibody
      • CD38H antibody
      • Cyclic ADP ribose hydrolase antibody
      • Cyclic ADP ribose hydrolase 1 antibody
      • Cyclic ADP-ribose hydrolase 1 antibody
      • EC 3.2.2.5 antibody
      • Ecto nicotinamide adenine dinucleotide glycohydrolase antibody
      • I-19 antibody
      • I19 (mouse) antibody
      • Lymphocyte differentiation antigen CD38 antibody
      • NAD(+) nucleosidase antibody
      • NIM-R5 antigen antibody
      • NIMR5 antigen (mouse) antibody
      • OTTHUMP00000158633 antibody
      • OTTHUMP00000217743 antibody
      • p45 antibody
      • T10 antibody
      see all

    Anti-CD38 antibody [FS02] (FITC) (ab1173)参考文献

    This product has been referenced in:
    • Zupo S  et al. CD38 signaling by agonistic monoclonal antibody prevents apoptosis of human germinal center B cells. Eur J Immunol 24:1218-22 (1994). Read more (PubMed: 8181532) »

    See 1 Publication for this product

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