概述

  • 产品名称Anti-CD35抗体[E11], prediluted
    参阅全部 CD35 一抗
  • 描述
    小鼠单克隆抗体[E11] to CD35, prediluted
  • 特异性Shows no cross-reaction with CD21. Strongly labels the follicular dendritic cells (FDC).
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human, Baboon, Rhesus monkey
  • 免疫原

    Intact human monocytes

  • 表位Distal from the C3b-binding site.
  • 阳性对照
    • Tonsil.
  • 常规说明


    Unable to block CD35 activity.

性能

应用

Our Abpromise guarantee covers the use of ab74318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/1. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Pre-diluted ready for use. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 mins, followed by cooling at RT for 20 mins.

靶标

  • 功能Mediates cellular binding of particles and immune complexes that have activated complement.
  • 组织特异性Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells.
  • 序列相似性Belongs to the receptors of complement activation (RCA) family.
    Contains 30 Sushi (CCP/SCR) domains.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C3 binding protein antibody
    • C3b/C4b receptor antibody
    • C3BR antibody
    • C4BR antibody
    • CD 35 antibody
    • CD35 antibody
    • CD35 antigen antibody
    • complement component (3b/4b) receptor 1 (Knops blood group) antibody
    • complement component (3b/4b) receptor 1 including Knops blood group system antibody
    • Complement component receptor 1 antibody
    • Complement receptor 1 antibody
    • Complement receptor type 1 antibody
    • CR 1 antibody
    • CR1 antibody
    • CR1_HUMAN antibody
    • KN antibody
    • Knops blood group antigen antibody
    see all

Anti-CD35 antibody [E11], prediluted 图像

  • Cell membrane staining of follicular dendritic cells, B cells and granulocytes in formalin-fixed, paraffin-embedded human tonsil tissue sections using ab74318 with a peroxidase-conjugated secondary antibody and a AEC chromogen.

Anti-CD35 antibody [E11], prediluted (ab74318)参考文献

This product has been referenced in:
  • Hogg N  et al. Identification of an anti-monocyte monoclonal antibody that is specific for membrane complement receptor type one (CR1). Eur J Immunol 14:236-43 (1984). Human . Read more (PubMed: 6368248) »

See 1 Publication for this product

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