PE Anti-CD34抗体[4H11(APG)],prediluted (ab18228)
Key features and details
- PE Mouse monoclonal [4H11(APG)] to CD34, prediluted
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
PE Anti-CD34抗体[4H11(APG)],prediluted
参阅全部 CD34 一抗 -
描述
PE小鼠单克隆抗体[4H11(APG)] to CD34,prediluted -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
The antibody reacts with Class III epitope on CD34 antibody. It completely blocks binding of Class II antibody QBEnd10 and Class III antibodies BIRMA K3 and 8G12 on KG1a cell line -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human CD34. Permanent human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia
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阳性对照
- CML cell line MOLM-7.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: PBS, BSA -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
Conjugate purified by size-exclusion chromatography. -
克隆
单克隆 -
克隆编号
4H11(APG) -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab18228于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt | (1) |
Use 20µl for 106 cells.
A cell suspension volume of 100 µl is recommended.
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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说明 |
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Flow Cyt
Use 20µl for 106 cells. A cell suspension volume of 100 µl is recommended.
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
靶标
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功能
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. -
组织特异性
Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. -
序列相似性
Belongs to the CD34 family. -
发展阶段
On early hematopoietic progenitor cells. -
翻译后修饰
Highly glycosylated.
Phosphorylated on serine residues by PKC. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 947 Human
- Omim: 142230 Human
- SwissProt: P28906 Human
- Unigene: 374990 Human
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别名
- CD34 antibody
- CD34 antigen antibody
- CD34 molecule antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab18228 被引用在 2 文献中.
- Sun KT et al. Reciprocal regulation of ?-globin expression by exo-miRNAs: Relevance to ?-globin silencing in ß-thalassemia major. Sci Rep 7:202 (2017). PubMed: 28303002
- Castro FV et al. 5T4 oncofetal antigen is expressed in high risk of relapse childhood pre-B acute lymphoblastic leukemia and is associated with a more invasive and chemotactic phenotype. Leukemia 26:1487-98 (2012). Flow Cyt ; Human . PubMed: 22266911