Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation.
Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.
Belongs to the CD300 family. Contains 1 Ig-like V-type (immunoglobulin-like) domain.