Anti-CD3 zeta抗体[H146-968] (Biotin) (ab113806)

概述

  • 产品名称Anti-CD3 zeta抗体[H146-968] (Biotin)
    参阅全部 CD3 zeta 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[H146-968] to CD3 zeta (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: WB, ELISA, Flow Cytmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Sheep, Rabbit, Chicken, Cow, Human, Pig, Cynomolgus Monkey
  • 免疫原

    Synthetic peptide:

    DTYDALHMQTLAPR

    , corresponding to amino acids 151-164 from Mouse CD3 zeta, conjugated to KLH.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituents: PBS, BSA
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明ab113806 was purified from ascitic fluid via Protein G Chromatography.
  • 克隆单克隆
  • 克隆编号H146-968
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab113806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 19 kDa.
ELISA Use at an assay dependent dilution.
Flow Cyt Use at an assay dependent dilution. (in permeabilized cells).

靶标

  • 功能Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
  • 疾病相关Defects in CD247 are the cause of immunodeficiency due to defect in CD3-zeta (CD3ZID) [MIM:610163]. An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens.
  • 序列相似性Belongs to the CD3Z/FCER1G family.
    Contains 3 ITAM domains.
  • 结构域The ITAM domains mediate interaction with SHB.
  • 翻译后修饰Phosphorylated on Tyr residues after T-cell receptor triggering.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 4930549J05Rik antibody
    • A430104F18Rik antibody
    • AW552088 antibody
    • CD247 antibody
    • CD247 antigen antibody
    • Cd247 molecule antibody
    • Cd3 antibody
    • CD3 antigen, zeta polypeptide, isoform CRA_b antibody
    • CD3 antigen, zeta subunit antibody
    • CD3-eta antibody
    • CD3H antibody
    • CD3Q antibody
    • Cd3z antibody
    • CD3Z antigen zeta polypeptide (TiT3 complex) antibody
    • CD3Z_HUMAN antibody
    • CD3zeta antibody
    • CD3zeta chain antibody
    • MGC140430 antibody
    • T cell receptor T3 zeta chain antibody
    • T cell surface glycoprotein CD3 zeta chain antibody
    • T-cell antigen receptor complex, zeta subunit of CD3 antibody
    • T-cell receptor T3 zeta chain antibody
    • T-cell surface glycoprotein CD3 zeta chain antibody
    • T3z antibody
    • TCR zeta chain antibody
    • TCRk antibody
    • TCRZ antibody
    • TCRzeta antibody
    see all

Anti-CD3 zeta antibody [H146-968] (Biotin) (ab113806)参考文献

ab113806 has not yet been referenced specifically in any publications.

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