Anti-CD3 epsilon抗体[C363.29B (YCD3-1)] (ab25469)

概述

• 产品名称Anti-CD3 epsilon抗体[C363.29B (YCD3-1)]
  参阅全部 CD3 epsilon 一抗
• 描述
  大鼠单克隆抗体[C363.29B (YCD3-1)] to CD3 epsilon
• 经测试应用适用于: Flow Cyt, IPmore details
• 种属反应性
  与反应: Mouse
  
• 免疫原

  The details of the immunogen for this antibody are not available.

• 表位This antibody recognises an epitope on the 25kDa epsilon chain of the CD3/TCR complex.
• 常规说明

  
  

  In the presence of Fc receptor-bearing accessory cells, this antibody can activate primed and naïve T cell in vitro. When immobilized it can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The antibody is cytolytic, is easily used for cell surface staining and is a good immunoprecipitating antibody. This antibody has shown to be useful in studies of in vitro depletion of CD3+ cells, and in vitro activation of T cells (accessory cells must be provided).

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
• 存储溶液pH: 8.20
  Constituent: 100% Borate buffered saline
• Concentration information loading...
• 纯度IgG fraction
• Primary antibody说明In the presence of Fc receptor-bearing accessory cells, this antibody can activate primed and naïve T cell in vitro. When immobilized it can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The antibody is cytolytic, is easily used for cell surface staining and is a good immunoprecipitating antibody. This antibody has shown to be useful in studies of in vitro depletion of CD3+ cells, and in vitro activation of T cells (accessory cells must be provided).
• 克隆单克隆
• 克隆编号C363.29B (YCD3-1)
• 同种型IgG2b
• 轻链类型kappa
• 研究领域
  • Immunology
  • Adaptive Immunity
  • T Cells
  • CD

  • Stem Cells
  • Hematopoietic Progenitors
  • Hematopoietic Stem Cells
  • Murine Lineage Negative

  • Stem Cells
  • Hematopoietic Progenitors
  • Lymphoid
  • T Lymphocytic Lineage

相关产品

• Compatible Secondaries
  • Goat Anti-Rat IgG H&L (Alexa Fluor® 488) (ab150157)
  • Goat Anti-Rat IgG H&L (HRP) (ab205720)

应用

靶标

• 功能The CD3 complex mediates signal transduction.
• 序列相似性Contains 1 Ig-like (immunoglobulin-like) domain.
  Contains 1 ITAM domain.
• 细胞定位Membrane.

• Target information above from: UniProt accession P07766 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 12501 Mouse
  • SwissProt: P22646 Mouse
  • Unigene: 210361 Mouse
• 别名
  • CD3 epsilon antibody
  • CD3e antibody
  • CD3e antigen epsilon polypeptide (TiT3 complex) antibody

  • CD3E antigen epsilon polypeptide antibody
  • CD3E antigen, epsilon subunit antibody
  • CD3e molecule epsilon antibody
  • CD3e molecule, epsilon (CD3 TCR complex) antibody
  • CD3e molecule, epsilon (CD3-TCR complex) antibody
  • CD3E_HUMAN antibody
  • IMD18 antibody
  • T cell antigen receptor complex epsilon subunit of T3 antibody
  • T cell surface antigen T3/Leu 4 epsilon chain antibody
  • T cell surface glycoprotein CD3 epsilon chain antibody
  • T-cell surface antigen T3/Leu-4 epsilon chain antibody
  • T-cell surface glycoprotein CD3 epsilon chain antibody
  • T3E antibody
  • TCRE antibody

  see all