概述
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产品名称Anti-CD3 epsilon抗体[C363.29B (YCD3-1)]
参阅全部 CD3 epsilon 一抗 -
描述大鼠单克隆抗体[C363.29B (YCD3-1)] to CD3 epsilon
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宿主Rat
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经测试应用适用于: Flow Cyt, IPmore details
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种属反应性与反应: Mouse
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免疫原
The details of the immunogen for this antibody are not available.
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表位This antibody recognises an epitope on the 25kDa epsilon chain of the CD3/TCR complex.
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常规说明
In the presence of Fc receptor-bearing accessory cells, this antibody can activate primed and naïve T cell in vitro. When immobilized it can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The antibody is cytolytic, is easily used for cell surface staining and is a good immunoprecipitating antibody. This antibody has shown to be useful in studies of in vitro depletion of CD3+ cells, and in vitro activation of T cells (accessory cells must be provided).
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
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存储溶液pH: 8.20
Constituent: 100% Borate buffered saline -
Concentration information loading... -
纯度Affinity purified
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Primary antibody说明In the presence of Fc receptor-bearing accessory cells, this antibody can activate primed and naïve T cell in vitro. When immobilized it can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The antibody is cytolytic, is easily used for cell surface staining and is a good immunoprecipitating antibody. This antibody has shown to be useful in studies of in vitro depletion of CD3+ cells, and in vitro activation of T cells (accessory cells must be provided).
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克隆单克隆
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克隆编号C363.29B (YCD3-1)
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同种型IgG2b
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轻链类型kappa
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研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab25469 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt | Use at an assay dependent concentration. ab18536 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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| IP | Use at an assay dependent concentration. |
靶标
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功能The CD3 complex mediates signal transduction.
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序列相似性Contains 1 Ig-like (immunoglobulin-like) domain.
Contains 1 ITAM domain. -
细胞定位Membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 12501 Mouse
- SwissProt: P22646 Mouse
- Unigene: 210361 Mouse
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别名
- CD3 epsilon antibody
- CD3e antibody
- CD3e antigen epsilon polypeptide (TiT3 complex) antibody
see all
文献
ab25469 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"