Anti-CD3 epsilon抗体[APA1/1] (Phycoerythrin) (ab91498)

概述

  • 产品名称Anti-CD3 epsilon抗体[APA1/1] (Phycoerythrin)
    参阅全部 CD3 epsilon 一抗
  • 描述
    小鼠单克隆抗体[APA1/1] to CD3 epsilon (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性ab91498 recognises an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Purified Human CD3 proteins isolated from thymus

  • 常规说明


    ab91498 provides the earliest known marker for TCR-mediated T cell activation.

性能

应用

Our Abpromise guarantee covers the use of ab91498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use a concentration of 5 µg/ml.

靶标

  • 功能The CD3 complex mediates signal transduction.
  • 序列相似性Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 1 ITAM domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD3 epsilon antibody
    • CD3e antibody
    • CD3e antigen epsilon polypeptide (TiT3 complex) antibody
    • CD3E antigen epsilon polypeptide antibody
    • CD3E antigen, epsilon subunit antibody
    • CD3e molecule epsilon antibody
    • CD3e molecule, epsilon (CD3 TCR complex) antibody
    • CD3e molecule, epsilon (CD3-TCR complex) antibody
    • CD3E_HUMAN antibody
    • IMD18 antibody
    • T cell antigen receptor complex epsilon subunit of T3 antibody
    • T cell surface antigen T3/Leu 4 epsilon chain antibody
    • T cell surface glycoprotein CD3 epsilon chain antibody
    • T-cell surface antigen T3/Leu-4 epsilon chain antibody
    • T-cell surface glycoprotein CD3 epsilon chain antibody
    • T3E antibody
    • TCRE antibody
    see all

Anti-CD3 epsilon antibody [APA1/1] (Phycoerythrin) (ab91498)参考文献

ab91498 has not yet been referenced specifically in any publications.

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