Anti-CD3 epsilon抗体[145-2C11] (Biotin) (ab114039)

概述

  • 产品名称Anti-CD3 epsilon抗体[145-2C11] (Biotin)
    参阅全部 CD3 epsilon 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[145-2C11] to CD3 epsilon (Biotin)
  • 偶联物Biotin
  • 特异性ab114039 is specific for a 25 kDa protein component (epsilon-T3) of the antigen specific T cell receptor in several Mouse strains. It reacts with all mature T cells and can both activate and inhibit T cell function.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    H-2Kb sp

  • 阳性对照
    • BALB/c Mouse thymocytes or splenic T Cells
  • 常规说明


    This monoclonal antibody, clone 145-2C11, was specifically designed to trigger T cell activation.

性能

应用

Our Abpromise guarantee covers the use of ab114039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 1µg for 106 cells.

靶标

  • 功能The CD3 complex mediates signal transduction.
  • 序列相似性Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 1 ITAM domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD3 epsilon antibody
    • CD3e antibody
    • CD3e antigen epsilon polypeptide (TiT3 complex) antibody
    • CD3E antigen epsilon polypeptide antibody
    • CD3E antigen, epsilon subunit antibody
    • CD3e molecule epsilon antibody
    • CD3e molecule, epsilon (CD3 TCR complex) antibody
    • CD3e molecule, epsilon (CD3-TCR complex) antibody
    • CD3E_HUMAN antibody
    • IMD18 antibody
    • T cell antigen receptor complex epsilon subunit of T3 antibody
    • T cell surface antigen T3/Leu 4 epsilon chain antibody
    • T cell surface glycoprotein CD3 epsilon chain antibody
    • T-cell surface antigen T3/Leu-4 epsilon chain antibody
    • T-cell surface glycoprotein CD3 epsilon chain antibody
    • T3E antibody
    • TCRE antibody
    see all

Anti-CD3 epsilon antibody [145-2C11] (Biotin) 图像

  • Flow cytometric analysis of CD3 epsilon in BALB/c thymocyte cells stained with ab114039 at 1 µg per 106 cells.
    Biotin Hamster IgG was used as isotypic control.
    Percentage of cells stained above control: 50.2%.
  • Flow Cytometric analysis of CD3 epsilon in BALB/c splenic T cells stained with ab114039 at 1 µg per 106 cells.
    Biotin Hamster IgG was used as isotypic control.
    Percentage of cells stained above control: 87.6%.

Anti-CD3 epsilon antibody [145-2C11] (Biotin) (ab114039)参考文献

This product has been referenced in:
  • Hirsch R  et al. Effects of in vivo administration of anti-T3 monoclonal antibody on T cell function in mice. I. Immunosuppression of transplantation responses. J Immunol 140:3766-72 (1988). Read more (PubMed: 3286764) »
  • Leo O  et al. Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc Natl Acad Sci U S A 84:1374-8 (1987). Read more (PubMed: 2950524) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab114039.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"