Anti-CD299抗体[MM0241- 2U25] (ab89183)

概述

  • 产品名称
    Anti-CD299抗体[MM0241- 2U25]
    参阅全部 CD299 一抗
  • 描述
    小鼠单克隆抗体[MM0241- 2U25] to CD299
  • 经测试应用
    适用于: Neutralising, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human recombinant CD299.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    purified from culture supernatant and 0.2 µm filter sterilised
  • 克隆
    单克隆
  • 克隆编号
    MM0241- 2U25
  • 同种型
    IgG2
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab89183 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Neutralising Use at an assay dependent concentration.
Flow Cyt 1/50 - 1/100. ab18414-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 功能
    Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens, including HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus protein S. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. Is presumably a coreceptor for the SARS coronavirus.
  • 组织特异性
    Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells.
  • 序列相似性
    Contains 1 C-type lectin domain.
  • 结构域
    The tandem repeat domain, also called neck domain, mediates oligomerization.
  • 细胞定位
    Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C type lectin domain family 4, member M antibody
    • C-type lectin domain family 4 member M antibody
    • CD209 antigen like antibody
    • CD209 antigen like protein 1 antibody
    • CD209 antigen-like protein 1 antibody
    • CD209L antibody
    • CD209L1 antibody
    • CD299 antibody
    • CD299 antigen antibody
    • CLC4M_HUMAN antibody
    • CLEC4M antibody
    • DC SIGN related protein antibody
    • DC SIGN2 antibody
    • DC SIGNR antibody
    • DC-SIGN-related protein antibody
    • DC-SIGN2 antibody
    • DC-SIGNR antibody
    • DCSIGN related protein antibody
    • DCSIGNR antibody
    • Dendritic cell-specific ICAM-3-grabbing non-integrin 2 antibody
    • HP10347 antibody
    • L SIGN antibody
    • L-SIGN antibody
    • Liver/lymph node specific ICAM3 grabbing nonintegrin antibody
    • Liver/lymph node-specific ICAM-3-grabbing non-integrin antibody
    • LSIGN antibody
    • Mannose binding C type lectin DC SIGNR antibody
    • MGC129964 antibody
    • MGC47866 antibody
    see all

文献

ab89183 has not yet been referenced specifically in any publications.

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