Anti-CD28抗体[CD28.2] - Low endotoxin, Azide free (ab85986)

概述

  • 产品名称Anti-CD28抗体[CD28.2] - Low endotoxin, Azide free
    参阅全部 CD28 一抗
  • 描述
    小鼠单克隆抗体[CD28.2] to CD28 - Low endotoxin, Azide free
  • 经测试应用适用于: WB, IP, IHC-Fr, Functional Studies, ICC, Flow Cytmore details
  • 种属反应性
    与反应: Human
    预测可用于: Non Human Primates
  • 免疫原

    Human CD28 transfected murine T cell hybridoma.

性能

应用

Our Abpromise guarantee covers the use of ab85986 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 25 kDa.
IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration.
ICC Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
  • 组织特异性Expressed in T-cells and plasma cells, but not in less mature B-cells.
  • 序列相似性Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 28 antibody
    • CD28 antibody
    • CD28 antigen antibody
    • CD28 molecule antibody
    • CD28_HUMAN antibody
    • MGC138290 antibody
    • T cell antigen CD28 antibody
    • T cell specific surface glycoprotein antibody
    • T cell specific surface glycoprotein CD28 antibody
    • T-cell-specific surface glycoprotein CD28 antibody
    • TP44 antibody
    see all

Anti-CD28 antibody [CD28.2] - Low endotoxin, Azide free 图像

  • Flow cytometry analysis of human peripheral blood leukocytes with anti-human CD28 (CD28.2) purified. 

Anti-CD28 antibody [CD28.2] - Low endotoxin, Azide free (ab85986)参考文献

This product has been referenced in:
  • Urso K  et al. NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis. Blood 118:795-803 (2011). Read more (PubMed: 21642596) »
  • Chen ML  et al. Antipsychotic drugs suppress the AKT/NF-?B pathway and regulate the differentiation of T-cell subsets. Immunol Lett 140:81-91 (2011). Functional Studies ; Human . Read more (PubMed: 21763349) »

See all 9 Publications for this product

Product Wall

Thank you for your inquiry.

We have one anti human CD28 antibody in our catalog that is tested and guaranteed for functional studies:

ab85986

http://www.abcam.com/index.html?datasheet=85986 (or use the following: http://ww...

Read More

Thank you for contacting us.

Ab85986 is produced using an immunogen ofHuman CD28 transfected murine T cell hybridoma. As such we do not have a specific peptide for immunogen blocking assay. I do apologize for any inconvenience this may cau...

Read More

Thanks for your call last week and for your patience while I have looked into your enquiry regarding ab85986. I heard back from the lab, and the binding of this antibody to CD28 mimics binding of CD80/86 to T cells, providing the cells with co-s...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"