Anti-CD21抗体[HI21a], prediluted (CF405M) (ab123615)

概述

  • 产品名称
    Anti-CD21抗体[HI21a], prediluted (CF405M)
    参阅全部 CD21 一抗
  • 描述
    小鼠单克隆抗体[HI21a] to CD21, prediluted (CF405M)
  • 偶联物
    CF405M. Ex: 408nm, Em: 452nm
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tonsil cells

  • 阳性对照
    • Normal Human peripheral blood cells.
  • 常规说明

    (Abs/Em Max: 408/450 nm) CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C.
  • 存储溶液
    pH: 7.20
    Preservative: 0.09% Sodium azide
    Note: Contains antibody stabilizing buffer.
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    单克隆
  • 克隆编号
    HI21a
  • 同种型
    IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab123615 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 5µl for 106 cells. ab126036-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 功能
    Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
  • 组织特异性
    Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
  • 疾病相关
    Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
  • 序列相似性
    Belongs to the receptors of complement activation (RCA) family.
    Contains 15 Sushi (CCP/SCR) domains.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C3DR antibody
    • CD 21 antibody
    • CD21 antibody
    • Complement C3d receptor 2 antibody
    • Complement C3d receptor antibody
    • Complement component (3d/Epstein Barr virus) receptor 2 antibody
    • Complement receptor type 2 antibody
    • CR antibody
    • Cr2 antibody
    • CR2_HUMAN antibody
    • CVID7 antibody
    • EBV receptor antibody
    • EBV-R antibody
    • Epstein Barr virus receptor antibody
    • Epstein-Barr virus receptor antibody
    • EVBR antibody
    • SLEB9 antibody
    see all

图片

  • ab123615, at 5 µl/106 cells, staining CD21 in normal Human peripheral blood cells by Flow Cytometry. Cells in the lymphocyte gate were used for analysis.

文献

ab123615 has not yet been referenced specifically in any publications.

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