概述

  • 产品名称Anti-CD20抗体[BV11], prediluted
    参阅全部 CD20 一抗
  • 描述
    兔单克隆抗体[BV11] to CD20, prediluted
  • 经测试应用适用于: IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide from the C-terminus of human CD20 protein.

  • 阳性对照
    • Human tonsil.

性能

应用

Our Abpromise guarantee covers the use of ab73095 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
IHC-Fr
  • 应用说明IHC-P: Use neat for 30-60 minutes at room temperature.
    IHC-Fr (acetone-fixed): Use neat for 30-60 minutes at room temperature.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能This protein may be involved in the regulation of B-cell activation and proliferation.
    • 组织特异性Expressed on B-cells.
    • 疾病相关Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
    • 序列相似性Belongs to the MS4A family.
    • 翻译后修饰Phosphorylated. Might be functionally regulated by protein kinase(s).
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • APY antibody
      • ATOPY antibody
      • B lymphocyte antigen CD20 antibody
      • B Lymphocyte Cell Surface Antigen B1 antibody
      • B-lymphocyte antigen CD20 antibody
      • B-lymphocyte cell-surface antigen B1 antibody
      • B-lymphocyte surface antigen B1 antibody
      • B1 antibody
      • Bp 35 antibody
      • Bp35 antibody
      • CD 20 antibody
      • CD20 antibody
      • CD20 antigen antibody
      • CD20 receptor antibody
      • CD20_HUMAN antibody
      • CVID5 antibody
      • Fc epsilon receptor I beta chain antibody
      • Fc Fragment of IgE high affinity I receptor for beta polypeptide antibody
      • FCER1B antibody
      • High affinity immunoglobulin epsilon receptor subunit beta antibody
      • IgE Fc receptor subunit beta antibody
      • IGEL antibody
      • IGER antibody
      • IGHER antibody
      • LEU 16 antibody
      • LEU16 antibody
      • leukocyte surface antigen Leu 16 antibody
      • Leukocyte surface antigen Leu-16 antibody
      • Ly44 antibody
      • Membrane spanning 4 domains A1 antibody
      • Membrane spanning 4 domains subfamily A member 2 antibody
      • Membrane-spanning 4-domains subfamily A member 1 antibody
      • MS4A1 antibody
      • MS4A2 antibody
      • S7 antibody
      see all

    Anti-CD20 antibody [BV11], prediluted 图像

    • ab73095 staining CD20 in human tonsils by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue.

    Anti-CD20 antibody [BV11], prediluted (ab73095)参考文献

    This product has been referenced in:
    • Groot Kormelink T  et al. Immunoglobulin free light chains are increased in hypersensitivity pneumonitis and idiopathic pulmonary fibrosis. PLoS One 6:e25392 (2011). IHC-P ; Human . Read more (PubMed: 21980441) »
    • Kormelink TG  et al. Decrease in immunoglobulin free light chains in patients with rheumatoid arthritis upon rituximab (anti-CD20) treatment correlates with decrease in disease activity. Ann Rheum Dis 69:2137-44 (2010). Read more (PubMed: 20679475) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab73095.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"