The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/2000. Detects a band of approximately 50 kDa (predicted molecular weight: 39 kDa).
1/250 - 1/500.
Is unsuitable for Flow Cyt,IHC-P or IP.
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Foster CT et al. Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics. Genes Dev31:2361-2375 (2017).
Read more (PubMed: 29317486) »
Boissard F et al. Nurse-like cells promote CLL survival through LFA-3/CD2 interactions. Oncotarget8:52225-52236 (2017).
Flow Cyt, ICC/IF
Read more (PubMed: 28881725) »